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阑尾疾病患者发生阑尾肿瘤的风险。

Risk of appendiceal neoplasm in patients with appendix disorders.

作者信息

Ferrara Francesco, Peltrini Roberto

机构信息

Department of Precision Medicine in Medical, Surgical and Critical Care (Me. Pre. C. C.), "Paolo Giaccone" Hospital, University of Palermo, Palermo 90127, Italy.

Department of Public Health, University of Naples Federico II, Napoli 80131, Italy.

出版信息

World J Clin Cases. 2024 Oct 6;12(28):6148-6150. doi: 10.12998/wjcc.v12.i28.6148.

DOI:10.12998/wjcc.v12.i28.6148
PMID:39371555
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11362891/
Abstract

The most common appendicular disease is acute appendicitis, with a lifetime risk of 7%-8%. Complicated cases, which can occur in 2%-7% of patients, can significantly impact the severity of the condition and may require different management approaches. Nonoperative management with possible delayed appendectomy has been suggested for selected patients, however, there is a non-negligible risk of missing an underlying malignancy, which is reported to be as high as 11%. Diagnostic work-up is paramount to achieve optimal treatment with good results.

摘要

最常见的阑尾疾病是急性阑尾炎,终生患病风险为7%-8%。复杂病例可发生在2%-7%的患者中,会显著影响病情的严重程度,可能需要不同的治疗方法。对于部分患者,有人建议采用可能延迟阑尾切除术的非手术治疗方法,然而,漏诊潜在恶性肿瘤的风险不可忽视,据报道这一风险高达11%。诊断检查对于实现最佳治疗效果至关重要。

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本文引用的文献

1
Appendiceal intussusception complicated by adenocarcinoma of the cecum: A case report.阑尾套叠并发盲肠腺癌:一例报告。
World J Clin Cases. 2024 Mar 16;12(8):1461-1466. doi: 10.12998/wjcc.v12.i8.1461.
2
Beyond acute appendicitis: a single-institution experience of unexpected pathology findings after 989 consecutive emergency appendectomy.超越急性阑尾炎:989 例连续急诊阑尾切除术后意外病理发现的单中心经验。
Langenbecks Arch Surg. 2024 Mar 5;409(1):87. doi: 10.1007/s00423-024-03277-0.
3
High Incidence of Appendiceal Neoplasms in the Elderly: A Critical Concern for Non-Surgical Treatment.老年人阑尾肿瘤发病率高:非手术治疗的关键问题。
Med Princ Pract. 2023;32(6):358-368. doi: 10.1159/000534347. Epub 2023 Oct 1.
4
Appendectomy during the COVID-19 pandemic in Italy: a multicenter ambispective cohort study by the Italian Society of Endoscopic Surgery and new technologies (the CRAC study).意大利 COVID-19 大流行期间的阑尾切除术:意大利内镜外科学和新技术学会(CRAC 研究)的多中心前瞻性队列研究。
Updates Surg. 2021 Dec;73(6):2205-2213. doi: 10.1007/s13304-021-01126-z. Epub 2021 Jul 4.
5
Risk of appendiceal neoplasm after interval appendectomy for complicated appendicitis: A systematic review and meta-analysis.间隔期阑尾切除术后并发阑尾炎患者发生阑尾肿瘤的风险:系统评价和荟萃分析。
Surgeon. 2021 Dec;19(6):e549-e558. doi: 10.1016/j.surge.2021.01.010. Epub 2021 Feb 25.
6
Increasing incidence of complicated appendicitis during COVID-19 pandemic.新冠疫情期间复杂性阑尾炎发病率上升。
Am J Surg. 2021 May;221(5):1056-1060. doi: 10.1016/j.amjsurg.2020.09.026. Epub 2020 Sep 28.
7
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J Trauma Acute Care Surg. 2020 Dec;89(6):1085-1091. doi: 10.1097/TA.0000000000002923.
8
Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines.急性阑尾炎的诊断和治疗:WSES 耶路撒冷指南 2020 年更新版。
World J Emerg Surg. 2020 Apr 15;15(1):27. doi: 10.1186/s13017-020-00306-3.
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Asian J Endosc Surg. 2020 Jul;13(3):311-318. doi: 10.1111/ases.12758. Epub 2019 Oct 16.
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JAMA. 2018 Sep 25;320(12):1259-1265. doi: 10.1001/jama.2018.13201.