Giorgio Antonio, De Luca Massimo
Athena Clinic Center, Via Matese, Piedimonte Matese (CE) 81016, Campania, Italy.
Liver Unit, AORN Cardarelli, Via A. Cardarelli, Napoli 80131, Campania, Italy.
World J Clin Cases. 2024 Oct 6;12(28):6241-6243. doi: 10.12998/wjcc.v12.i28.6241.
This manuscript is based on a case reported by Song published in the . Several challenges remain in the field of hepatocellular carcinoma (HCC) conversion therapy. Consequently, only a limited number of patients with HCC accompanied by portal vein tumor thrombosis (PVTT) and hepatic vein tumor thrombosis (HVTT) are eligible for resection. This clinical case demonstrates that considering the complexity of the disease, a multimodal and multidisciplinary approach is essential for managing HCC accompanied by PVTT and HVTT. However, the outcomes of such surgeries remain controversial. In conclusion, research on HCC conversion therapy is extremely useful for improving treatment strategies for intermediate and advanced HCC, which currently have disappointing clinical outcomes.
本手稿基于宋发表在……上报告的一个病例。肝细胞癌（HCC）转化治疗领域仍存在若干挑战。因此，仅有有限数量伴有门静脉癌栓（PVTT）和肝静脉癌栓（HVTT）的HCC患者适合进行手术切除。该临床病例表明，鉴于疾病的复杂性，多模式和多学科方法对于管理伴有PVTT和HVTT的HCC至关重要。然而，此类手术的结果仍存在争议。总之，HCC转化治疗的研究对于改善中晚期HCC的治疗策略极为有用，目前中晚期HCC的临床结果令人失望。
