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1例接受阿达木单抗作为化脓性汗腺炎免疫抑制治疗的患者发生脑膜炎奈瑟菌感染的病例报告

A Presentation of Neisseria meningitidis in a Patient Taking Adalimumab as Immunosuppressive Therapy for Hidradenitis Suppurativa.

作者信息

Bolling Jacob W, Holley Aaron D, Rogers Cleon

机构信息

Medicine, Christ Health Center, Edward Via College of Osteopathic Medicine, Birmingham, USA.

Internal Medicine, Christ Health Center, Birmingham, USA.

出版信息

Cureus. 2024 Sep 4;16(9):e68628. doi: 10.7759/cureus.68628. eCollection 2024 Sep.

DOI:10.7759/cureus.68628
PMID:39371773
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11451091/
Abstract

is common within the human population. Most patients with  colonization are asymptomatic, but invasive disease can result in meningitis, fulminant septicemia, and disseminated intravascular coagulation. This case report describes a patient who presented with symptoms of sepsis and was later diagnosed with . The cause of her infection was believed to be immunosuppression from adalimumab, which she was taking for systemic hidradenitis suppurativa.

摘要

在人群中很常见。大多数携带[病原体名称未给出]的患者没有症状，但侵袭性疾病可导致脑膜炎、暴发性败血症和弥散性血管内凝血。本病例报告描述了一名出现败血症症状的患者，后来被诊断为[疾病名称未给出]。据信她感染的原因是正在服用的用于治疗化脓性汗腺炎的阿达木单抗导致的免疫抑制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53c0/11451091/4aa0d1dd4e5d/cureus-0016-00000068628-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53c0/11451091/4aa0d1dd4e5d/cureus-0016-00000068628-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53c0/11451091/4aa0d1dd4e5d/cureus-0016-00000068628-i01.jpg

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