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多囊性脑病：缺血缺氧性损伤的最终表现。

Multicystic encephalopathy: an ultimate manifestation of ischemic-hypoxic injury.

作者信息

Aragones Vielka Fernandez, Castellano-Sanchez Amilcar, Chamyan Gabriel, Santana-Acosta Darline

机构信息

Mount Sinai Medical Center, Arkadi M. Rywlin Department of Pathology and Laboratory Medicine, Miami Beach, FL, USA.

Florida International University, Herbert Wertheim College of Medicine, Department of Pathology, Miami, FL, USA.

出版信息

Autops Case Rep. 2024 Sep 27;14:e2024517. doi: 10.4322/acr.2024.517. eCollection 2024.

DOI:10.4322/acr.2024.517
PMID:39372076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11452078/
Abstract

Multicystic encephalopathy is a rare neurological finding characterized by the appearance of multiple cystic or cavitary lesions as the result of repetitive episodes of hypoxic-ischemic injury in neonates and infants. We present a rare case of multicystic encephalopathy in a 3-month-old male, born at 34 weeks with Tetralogy of Fallot and multiple comorbidities. Gross examination of the brain during the autopsy revealed multiple irregular cystic lesions and distortion of the brain parenchyma. This case report highlights the uniqueness of multicystic encephalopathy and offers an extensive review of the existing literature, including etiology, clinical presentation, and histopathologic findings.

摘要

多囊性脑病是一种罕见的神经学表现，其特征是新生儿和婴儿因反复发生缺氧缺血性损伤而出现多个囊性或空洞性病变。我们报告一例罕见的3个月大男性多囊性脑病病例，该患儿34周出生，患有法洛四联症及多种合并症。尸检时对大脑进行大体检查发现多个不规则囊性病变及脑实质变形。本病例报告突出了多囊性脑病的独特性，并对现有文献进行了广泛综述，包括病因、临床表现和组织病理学发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/2646b56a1d7c/autopsy-14-e2024517-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/05b1980af2d8/autopsy-14-e2024517-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/cd81aec6fef8/autopsy-14-e2024517-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/49c518ec64ca/autopsy-14-e2024517-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/ed964ecd4593/autopsy-14-e2024517-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/7807e865cc92/autopsy-14-e2024517-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/2646b56a1d7c/autopsy-14-e2024517-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/05b1980af2d8/autopsy-14-e2024517-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/cd81aec6fef8/autopsy-14-e2024517-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/49c518ec64ca/autopsy-14-e2024517-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/ed964ecd4593/autopsy-14-e2024517-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/7807e865cc92/autopsy-14-e2024517-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b8/11452078/2646b56a1d7c/autopsy-14-e2024517-g06.jpg

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本文引用的文献

1
Multicystic encephalomalacia: An autopsy report of 4 cases.多囊性脑软化症：4例尸检报告
Autops Case Rep. 2020 Nov 20;10(4):e2020208. doi: 10.4322/acr.2020.208.
2
Severe Brain Malformations in an Infant With Pyruvate Dehydrogenase Deficiency and Down Syndrome.一名患有丙酮酸脱氢酶缺乏症和唐氏综合征婴儿的严重脑畸形
Pediatr Neurol. 2017 Oct;75:101-102. doi: 10.1016/j.pediatrneurol.2017.05.002. Epub 2017 May 8.
3
Multicystic encephalomalacia secondary to head trauma.头部外伤继发的多囊性脑软化症
J Neurosci Rural Pract. 2017 Jan-Mar;8(1):158-159. doi: 10.4103/0976-3147.193528.
4
Multicystic encephalopathy in abusive head trauma.虐待性头部创伤中的多囊性脑病
Clin Neuropathol. 2014 Jul-Aug;33(4):299-307. doi: 10.5414/NP300700.
5
Multicystic encephalopathy following prolonged hypoxic ischemic insult--a case report.长时间缺氧缺血性损伤后的多囊性脑病——病例报告
Childs Nerv Syst. 2012 Jun;28(6):947-50. doi: 10.1007/s00381-011-1671-y. Epub 2012 Jan 21.
6
Multicystic encephalomalacia as an end-stage finding in abusive head trauma.多囊性脑软化作为虐待性头部外伤的终末期表现。
Forensic Sci Med Pathol. 2011 Dec;7(4):355-63. doi: 10.1007/s12024-011-9236-7. Epub 2011 Apr 26.
7
Human toxoplasmosis; a clinicopathologic study with presentation of five cases and review of the literature.人类弓形虫病：一项包含五例病例报告及文献综述的临床病理研究
Medicine (Baltimore). 1946 Dec;25(4):343-97. doi: 10.1097/00005792-194612000-00001.
8
Body Length and Organ Weights of Infants and Children: A Study of the Body Length and Normal Weights of the More Important Vital Organs of the Body between Birth and Twelve Years of Age.婴幼儿及儿童的身长与器官重量：一项关于出生至12岁期间身体更重要生命器官的身长及正常重量的研究。
Am J Pathol. 1933 Jan;9(1):55-70.
9
Diffuse multicystic encephalomalacia in a preterm baby due to homozygous methylenetetrahydrofolate reductase 677 C-->T mutation.
J Child Neurol. 2008 Jun;23(6):695-8. doi: 10.1177/0883073807312371.
10
The cerebral atrophies and encephalomalacias of infancy and childhood.婴幼儿期的脑萎缩和脑软化
Res Publ Assoc Res Nerv Ment Dis. 1955;34:199-330.