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无临床症状的甲状旁腺癌:一例报告及文献复习

PARATHYROID CARCINOMA WITH LACK OF CLINICAL SYMPTOMS: A CASE REPORT AND REVIEW OF LITERATURE.

作者信息

Zhou R

机构信息

The Second People's Hospital of Yibin, Yibin, China.

出版信息

Acta Endocrinol (Buchar). 2024 Jan-Mar;20(1):103-106. doi: 10.4183/aeb.2024.103. Epub 2024 Oct 3.

Abstract

CONTEXT

Parathyroid carcinomas (PC) are rare. Imaging and laboratory tests can suggest a diagnosis of PC, but pathological examination is ultimately required to confirm the diagnosis.

OBJECTIVE

The clinicopathologic data, diagnosis, and treatment of a case of PC diagnosed in our hospital in 2022 are retrospectively summarized in this case report to improve the understanding, diagnosis, and differential diagnosis of this disease.

DESIGN

Case report.

SUBJECTS AND METHODS

Herein, we present the case of a 35-year-old man who presented with imaging and laboratory findings suggestive of a parathyroid neoplasm.

RESULTS

The patient underwent radical resection of the tumor, which was histopathologically diagnosed as PC.

CONCLUSION

In this case, the clinical manifestations of PC were insidious, and the histological features had to be differentiated from tumors, such as parathyroid adenoma, clear cell renal cell carcinoma, and medullary thyroid carcinoma; thus, its diagnosis was challenging.

摘要

背景

甲状旁腺癌(PC)较为罕见。影像学和实验室检查可提示PC的诊断,但最终确诊仍需病理检查。

目的

本病例报告回顾性总结了2022年我院诊断的1例PC的临床病理资料、诊断及治疗情况,以提高对该病的认识、诊断及鉴别诊断能力。

设计

病例报告。

研究对象与方法

本文报告1例35岁男性患者,其影像学和实验室检查结果提示甲状旁腺肿瘤。

结果

患者接受了肿瘤根治性切除术,术后病理诊断为PC。

结论

本例中,PC的临床表现隐匿,其组织学特征必须与甲状旁腺腺瘤、透明细胞肾细胞癌和甲状腺髓样癌等肿瘤相鉴别,因此其诊断具有挑战性。

相似文献

本文引用的文献

1
Contemporary Evaluation and Management of Parathyroid Carcinoma.甲状旁腺癌的当代评估与管理。
JCO Oncol Pract. 2021 Jan;17(1):17-21. doi: 10.1200/JOP.19.00540. Epub 2020 Feb 10.
4
Parathyroid Carcinoma.甲状旁腺癌。
Front Horm Res. 2019;51:63-76. doi: 10.1159/000491039. Epub 2018 Nov 19.
7
Update on parathyroid carcinoma.甲状旁腺癌的最新进展。
J Endocrinol Invest. 2016 Jun;39(6):595-606. doi: 10.1007/s40618-016-0447-3. Epub 2016 Mar 21.
8
Parathyroid: The Pathology of Hyperparathyroidism.甲状旁腺:甲状旁腺功能亢进的病理学
Surg Pathol Clin. 2014 Dec;7(4):515-31. doi: 10.1016/j.path.2014.08.004. Epub 2014 Oct 6.
10
Is central lymph node dissection necessary for parathyroid carcinoma?甲状旁腺癌是否需要进行中央淋巴结清扫?
Surgery. 2014 Dec;156(6):1336-41; discussion 1341. doi: 10.1016/j.surg.2014.08.005. Epub 2014 Nov 11.

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