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尼日利亚伊巴丹感染艾滋病毒女性生育进展相关因素的多州模型

Multistate model for correlates of parity progression among women living with HIV in Ibadan, Nigeria.

作者信息

Olagunju Ahmed, Akinyemi Joshua O, Afolabi Rotimi, Awolude Olutosin A

机构信息

Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Universidade do Algarve, Faro, Portugal.

出版信息

Res Sq. 2024 Sep 17:rs.3.rs-4927011. doi: 10.21203/rs.3.rs-4927011/v1.

Abstract

Globally, childbearing is a major concern for women living with HIV (WLWH). This study examined parity progression and its predictors among WLWH in Ibadan, Southwest Nigeria. We analysed dataset from a cross-sectional study on childbearing progression among 933 respondents aged 18-49 years receiving care at the HIV Program, University College Hospital, Ibadan. Multistate model was employed for analysis. The adjusted total fertility rate was 3.54. More than 70% were likely to progress from first-to-second birth (HR = 1.77; CI: 1.40, 2.23)but none of the covariates analysed were associated with progression. WLWH were less likely of progression from second-to-third birth (HR = 0.14; 95% CI: 0.13, 0.16). Having 1-2 children at HIV diagnosis (HR = 0.59; CI: 0.48, 0.71), being widowed (HR = 1.36; CI: 1.04, 1.80), having a partner with secondary education(HR = 1.23; 95% CI: 1.02, 1.49), partner's employment status (HR = 1.40; 95% CI: 1.04, 1.80), , knowledge of partner's HIV status (Negative) (HR = 0.75; 95% CI: 0.61, 0.94) were associated with progression to third birth. The estimated total fertility rate was lower than the national and the Southwest estimates. Different factors were associated with birth progression from one parity to another.

摘要

在全球范围内,生育是感染艾滋病毒的女性(WLWH)主要关心的问题。本研究调查了尼日利亚西南部伊巴丹感染艾滋病毒女性的生育进展情况及其预测因素。我们分析了一项关于生育进展的横断面研究数据集,该研究涉及933名年龄在18至49岁之间、在伊巴丹大学学院医院艾滋病毒项目接受治疗的受访者。采用多状态模型进行分析。调整后的总生育率为3.54。超过70%的人可能从第一胎生育进展到第二胎生育(风险比=1.77;置信区间:1.40,2.23),但所分析的协变量均与生育进展无关。感染艾滋病毒的女性从第二胎生育进展到第三胎生育的可能性较小(风险比=0.14;95%置信区间:0.13,0.16)。艾滋病毒诊断时已有1-2个孩子(风险比=0.59;置信区间:0.48,0.71)、丧偶(风险比=1.36;置信区间:1.04,1.80)、伴侣接受过中等教育(风险比=1.23;95%置信区间:1.02,1.49)、伴侣的就业状况(风险比=1.40;95%置信区间:1.04,1.80)、知晓伴侣的艾滋病毒感染状况(阴性)(风险比=0.75;95%置信区间:0.61,0.94)与生育第三胎有关。估计的总生育率低于全国和西南部的估计水平。不同因素与不同胎次间的生育进展有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da5/11451636/575bce853e09/nihpp-rs4927011v1-f0001.jpg

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