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Antiepileptic drugs, folate one-carbon metabolism, genetics, and epigenetics: Congenital, developmental, and neuropsychological risks and antiepileptic action.

作者信息

Reynolds Edward H

机构信息

Department of Clinical Neurosciences, Kings College London, London, UK.

出版信息

Epilepsia. 2024 Dec;65(12):3469-3473. doi: 10.1111/epi.18120. Epub 2024 Oct 7.

DOI:10.1111/epi.18120
PMID:39373638
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11647427/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3987/11647427/f13a23828cc8/EPI-65-3469-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3987/11647427/f13a23828cc8/EPI-65-3469-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3987/11647427/f13a23828cc8/EPI-65-3469-g001.jpg

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本文引用的文献

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Cell Discov. 2023 Feb 28;9(1):22. doi: 10.1038/s41421-022-00512-0.
2
Folic acid inhibits 5-methyltetrahydrofolate transport across the blood-cerebrospinal fluid barrier: Clinical biochemical data from two cases.叶酸抑制5-甲基四氢叶酸跨血脑脊髓液屏障的转运：两例临床生化数据
JIMD Rep. 2022 Aug 6;63(6):529-535. doi: 10.1002/jmd2.12321. eCollection 2022 Nov.
3
Folic Acid and the Prevention of Birth Defects: 30 Years of Opportunity and Controversies.
叶酸与出生缺陷预防：30 年的机遇与争议
Annu Rev Nutr. 2022 Aug 22;42:423-452. doi: 10.1146/annurev-nutr-043020-091647.
4
Transgenerational adverse effects of valproate? A patient report from 90 affected families.丙戊酸盐的跨代不良反应？来自90个受影响家庭的病例报告。
Birth Defects Res. 2022 Jan 1;114(1):13-16. doi: 10.1002/bdr2.1967. Epub 2021 Dec 5.
5
Anemia and Vitamin B-12 and Folate Status in Women of Reproductive Age in Southern India: Estimating Population-Based Risk of Neural Tube Defects.印度南部育龄妇女的贫血状况以及维生素B-12和叶酸水平：评估基于人群的神经管缺陷风险
Curr Dev Nutr. 2021 Apr 26;5(5):nzab069. doi: 10.1093/cdn/nzab069. eCollection 2021 May.
6
Antiepileptic drugs, folate and one carbon metabolism revisited.抗癫痫药物、叶酸与一碳代谢再探讨。
Epilepsy Behav. 2020 Nov;112:107336. doi: 10.1016/j.yebeh.2020.107336. Epub 2020 Aug 29.
7
-Adenosine Methionine (SAMe) and Valproic Acid (VPA) as Epigenetic Modulators: Special Emphasis on their Interactions Affecting Nervous Tissue during Pregnancy.腺苷蛋氨酸（SAMe）和丙戊酸（VPA）作为表观遗传调节剂：特别强调它们在怀孕期间对神经组织的相互作用。
Int J Mol Sci. 2020 May 25;21(10):3721. doi: 10.3390/ijms21103721.
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Epilepsy Behav. 2020 Jul;108:107068. doi: 10.1016/j.yebeh.2020.107068. Epub 2020 May 3.
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