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使用头孢地尔成功治疗一名患有嗜麦芽窄食单胞菌医院获得性肺炎的新生儿。

Successful therapy of a newborn with Stenotrophomonas maltophilia nosocomial pneumonia with cefiderocol.

作者信息

Trauth Janina, Schuler Rahel, Waitz Markus, Ehrhardt Harald, Fritzenwanker Moritz, Herold Susanne

机构信息

Department of Medicine V - Internal Medicine, Infectious Diseases & Infection Control, Justus- Liebig-University, member of the German Center for Lung Research (DZL) and German Center for Infection Research (DZIF) and Cardio-Pulmonary Institute (CPI), Giessen, Germany.

Department of General Pediatrics and Neonatology, Justus Liebig University, Giessen, Germany.

出版信息

Infection. 2025 Jun;53(3):1227-1231. doi: 10.1007/s15010-024-02404-9. Epub 2024 Oct 7.

Abstract

Cefiderocol is a new siderophore-beta-lactam antibiotic used for the treatment of severe multidrug-resistant infections like sepsis, hospital-acquired and ventilator-associated pneumonia in adults, but there are only single reports on its use in the neonatal population. We describe the successful cefiderocol treatment of a newborn with pneumogenic sepsis due to Stenotrophomonas maltophilia.

摘要

头孢地尔是一种新型的铁载体β-内酰胺类抗生素,用于治疗严重的多重耐药感染,如成人败血症、医院获得性肺炎和呼吸机相关性肺炎,但关于其在新生儿群体中的应用仅有个别报道。我们描述了一例因嗜麦芽窄食单胞菌导致肺源性败血症的新生儿成功接受头孢地尔治疗的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fa3/12137400/a53392b135ef/15010_2024_2404_Fig1_HTML.jpg

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