Dubois J B
Bull Cancer. 1985;72(6):549-58.
A finer analysis of the spontaneous evolution of prostatic cancer has led to a better understanding of the importance of a long period of lymph node extension without necessarily concomitant distant metastases. Advances in interstitial brachytherapy and external irradiation technique have led to satisfactory local control, a low incidence of local recurrent disease, a large number of histologically sterile samples upon repeat biopsy, fewer complications and a 5 and 10 year survival rate unsurpassed by any alternative therapy. A comparison between radiotherapy and radical prostatectomy shows comparable therapeutic efficacy for stages A and B1 but a superior local control, higher survival rate at 5 and 10 years and fewer complications for irradiation at stages B2 and C. The irradiated volume and optimal doses have yet to be established. After a description of irradiation and dosimetric techniques, we will discuss the place of present-day radiotherapy in curative locoregional treatment of prostatic cancer.
对前列腺癌自然发展过程进行更精细的分析，使人们更好地理解了淋巴结长期扩散而不一定伴有远处转移的重要性。间质近距离放疗和外照射技术的进步已带来了令人满意的局部控制效果、局部复发性疾病的低发生率、重复活检时大量组织学上无菌的样本、更少的并发症以及5年和10年生存率，这是任何其他替代疗法都无法超越的。放疗与根治性前列腺切除术的比较表明，对于A期和B1期，两者的治疗效果相当，但对于B2期和C期，放疗在局部控制方面更优，5年和10年生存率更高，并发症更少。照射体积和最佳剂量尚未确定。在描述了放疗和剂量测定技术之后，我们将讨论当今放疗在前列腺癌根治性局部区域治疗中的地位。
