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双表型鼻窦肉瘤——病例系列及文献综述

Biphenotypic Sinonasal Sarcoma- A case Series with a Review of Literature.

作者信息

Chaturvedi Anubhuti, Kumari Gauri, Dhankar Nimisha, Mallya Varuna, Mandal Shramana, Meher Ravi

机构信息

Department of Pathology, Pathology Block, Maulana Azad Medical College and Lok Nayak Hospital, Room 57, New Delhi, 110002 India.

Department of Otolaryngology, Maulana Azad Medical Collegeand Lok Nayak Hospital, New Delhi, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4776-4780. doi: 10.1007/s12070-024-04844-z. Epub 2024 Jul 6.

Abstract

Biphenotypic sinonasal sarcoma (BSNS) is a rare malignant tumor that affects the upper nasal cavity and ethmoid sinuses. It is more commonly found in middle-aged women and is characterized by the infiltration and hypercellular proliferation of spindle cells. These cells exhibit specific immunoreactivity. We add seven cases diagnosed as BSNS, to the handful of cases already available in the literature.BSNS is a malignant disease of the sinonasal tract that requires prompt and accurate diagnosis, followed by surgical resection and consideration of radiotherapy. Our analysis of seven cases supports previous research that confirms the aggressive nature of the disease but also shows that it is treatable with the right approach.

摘要

双表型鼻窦肉瘤(BSNS)是一种罕见的恶性肿瘤,累及上鼻腔和筛窦。它更常见于中年女性,其特征是梭形细胞浸润和细胞过度增殖。这些细胞表现出特定的免疫反应性。我们在文献中已有的少数病例基础上,又增加了7例诊断为BSNS的病例。BSNS是鼻窦道的一种恶性疾病,需要及时准确的诊断,随后进行手术切除并考虑放疗。我们对7例病例的分析支持了先前的研究,该研究证实了这种疾病的侵袭性,但也表明采用正确的方法是可以治疗的。

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