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奥替尼啶漱口水:治疗急性咽炎的福音。

Octinidine Gargles: A Boon in a Treatment of Acute Pharyngitis.

作者信息

Agrawal Ayush, Shubhanshu Kumar

机构信息

Department of Otorhinolaryngology, HIMS, Sitapur, Uttar Pradesh India.

Department of Otorhinolaryngology, CIMS, Lucknow, Uttar Pradesh India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4230-4233. doi: 10.1007/s12070-024-04820-7. Epub 2024 Jun 18.

Abstract

Pharyngitis is a disorder commonly reported in ENT OPDs. The most common cause of Pharyngitis in India is Group A streptococcus, with prevalence rates of 13% in children aged 5-15%. It can also be attributed to various other bacterial, viral and fungal agents. Oral gargles are increasingly being used as a safe, effective, and non-invasive method for management. The aim of the present study was to evaluate the efficacy of Octenidine gargles in cases of Acute Pharyngitis. The present study is a prospective double blinded randomised study done in a tertiary care hospital in Sitapur, UP between 1st January, 2022 to 30th June, 2022. Patients with acute pharyngitis were randomised into two groups- Octenidine and Placebo group and subsequently, the efficacy of octenidine was studied. The octenidine gargle group reported better improvement acute pharyngitis symptoms and a significantly shorter time to symptom resolution. The study suggests that Octenidine gargles are an effective treatment option for Acute Pharyngitis, providing significant symptom relief and a shorter time to resolution when compared to warm saline gargles.

摘要

咽炎是耳鼻喉科门诊中常见的病症。在印度,咽炎最常见的病因是A组链球菌,5至15岁儿童中的患病率为13%。它也可能归因于各种其他细菌、病毒和真菌病原体。口腔含漱液越来越多地被用作一种安全、有效且无创的治疗方法。本研究的目的是评估奥替尼啶含漱液治疗急性咽炎的疗效。本研究是一项前瞻性双盲随机研究,于2022年1月1日至2022年6月30日在北方邦锡塔布尔的一家三级护理医院进行。患有急性咽炎的患者被随机分为两组——奥替尼啶组和安慰剂组,随后对奥替尼啶的疗效进行了研究。奥替尼啶含漱液组在急性咽炎症状改善方面表现更佳,症状缓解时间显著缩短。该研究表明,与温盐水含漱相比,奥替尼啶含漱液是治疗急性咽炎的一种有效选择,能显著缓解症状并缩短症状缓解时间。

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