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花瓣样技术及光学相干断层扫描对全层黄斑裂孔黄斑裂孔形态的预后意义

Petaloid technique and prognostic significance of macular hole shapes by optical coherence tomography for full thickness macular hole.

作者信息

Keyal Khusbu, Li Bing, Liu Chunyu, Tian Zhongping, Li Houshuo, Bi Yanlong

机构信息

Department of Ophthalmology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.

出版信息

Front Med (Lausanne). 2024 Sep 23;11:1424580. doi: 10.3389/fmed.2024.1424580. eCollection 2024.

Abstract

Surgical advancements for full-thickness macular hole (FTMH) treatment include vitrectomy, membrane peeling, and the inverted flap technique (IFT). IFT, which involves inverting the internal limiting membrane (ILM) flap over the macular hole (MH) or into the MH, improves success rates and visual recovery. However, issues like mis-aspiration during flap handling have been problematic. We introduce the petaloid technique, to position the ILM flap under air during FTMH surgery to evaluate its outcomes. This retrospective study included 28 eyes, with a mean minimum linear diameter (MLD) 472.04 ± 199.7 μm and basal diameter (BD) of 834.95 ± 593.54 μm. Primary closure of MH was achieved in 96.42% of patients, with 3.57% showing persistent MH during the 6-month follow-up. The VA improved significantly from preoperative levels at each postoperative stage, with notable increases at 3 months (0.86 ± 0.49 logMAR;  = 0.0132) and 6 months (0.77 ± 0.41 logMAR;  = 0.000081). The new closure patterns showed Type A in 28.6%, B in 14.3%, C in 28.6%, and D in 25%. Among different types of closure patterns, although VA improved in all types, significant improvement in VA was noted for type A and type C, with notable improvements at the 6-month follow-up for Type A (0.60 ± 0.23 logMAR;  = 0.02) and at the 1-month follow-up for Type C (0.62 ± 0.28 logMAR; p = 0.02). For macular hole retinal detachment in 5 eyes, the average preoperative VA was 1.86 ± 0.19 logMAR, while the final mean postoperative VA showed a significant improvement to 1.1 ± 0.40 logMAR ( = 0.021, paired -tests). Retinal reattachment was achieved in all cases (5/5) without recurrent detachment post-silicone oil removal. For the prognostic significance of MH shapes identified by OCT, it can be concluded that the shape of macular holes significantly influences visual acuity outcomes at 6 months post-surgery ( = 0.037). The shape of macular holes, particularly Flask-shaped, significantly impacts visual acuity compared to other shape. The modified petaloid technique for treating FTMH proved safe and effective, with no significant complications noted.

摘要

全层黄斑裂孔(FTMH)治疗的手术进展包括玻璃体切除术、膜剥除术和反转瓣技术(IFT)。IFT是将内界膜(ILM)瓣反转覆盖在黄斑裂孔(MH)上或置入MH内,可提高成功率和视力恢复情况。然而,瓣操作过程中的误抽吸等问题一直存在。我们引入花瓣状技术,在FTMH手术中于空气下放置ILM瓣以评估其效果。这项回顾性研究纳入了28只眼,平均最小线性直径(MLD)为472.04±199.7μm,基底直径(BD)为834.95±593.54μm。96.42%的患者实现了MH的一期闭合,3.57%的患者在6个月随访期间显示MH持续存在。术后各阶段视力均较术前显著提高,在3个月(0.86±0.49 logMAR;p = 0.0132)和6个月(0.77±0.41 logMAR;p = 0.000081)时提高显著。新的闭合模式中,A型占28.6%,B型占14.3%,C型占28.6%,D型占25%。在不同类型的闭合模式中,尽管所有类型的视力均有提高,但A型和C型视力有显著改善,A型在6个月随访时(0.60±0.23 logMAR;p = 0.02)和C型在1个月随访时(0.62±0.28 logMAR;p = 0.02)改善显著。对于5只眼的黄斑裂孔性视网膜脱离,术前平均视力为1.86±0.19 logMAR,而术后最终平均视力显著提高至1.1±0.40 logMAR(p = 0.021,配对t检验)。所有病例(5/5)均实现视网膜复位,硅油取出后无复发性脱离。对于OCT识别的MH形状的预后意义,可以得出结论,黄斑裂孔的形状在术后6个月对视力结果有显著影响(p = 0.037)。与其他形状相比,黄斑裂孔的形状,尤其是烧瓶状,对视力有显著影响。改良花瓣状技术治疗FTMH被证明是安全有效的,未发现显著并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/408e/11456521/4aaddaacdf43/fmed-11-1424580-g001.jpg

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