Konishi Kazuhisa, Tanaka Toshiyuki, Yamamoto Kohei, Tsuji Taisuke, Takumi Chieko
Respiratory Medicine, Japanese Red Cross Society Kyoto Daiichi Hospital, Kyoto, JPN.
Cureus. 2024 Sep 6;16(9):e68840. doi: 10.7759/cureus.68840. eCollection 2024 Sep.
A 64-year-old man visited our outpatient clinic with chief complaints of high fever and throat pain. His medical history was significant for pulmonary amyloidosis that was observed at our outpatient clinic, and his recent recovery from COVID-19. Findings from imaging studies included thickening of the bronchial walls, infiltrates of the left upper lobe, and pre-existing pulmonary nodules from amyloidosis. A peripheral blood examination revealed leukocytosis and elevated C-reactive protein levels. His signs and symptoms suggested bronchopneumonia and antimicrobial treatment was initiated. Sputum microscopic examination revealed gram-negative cocci and culture growth revealed to be , with follow-up bacterial specimens after treatment demonstrating diminished microbes. Despite a medical history of amyloidosis and COVID-19, the patient's clinical course resulted in favorable outcomes. The infection is a rare condition in generally healthy individuals, and certain conditions may be related to the contraction of the pathogen, otherwise seen primarily in immunocompromised hosts. In our case, the medical history of amyloidosis and recent COVID-19 infection may have contributed to the development of meningococcal bronchopneumonia.
一名64岁男性因高热和咽痛为主诉前来我院门诊就诊。他有在我院门诊确诊的肺淀粉样变性病史，且近期从新冠病毒感染中康复。影像学检查结果包括支气管壁增厚、左上叶浸润以及淀粉样变性所致的既往肺部结节。外周血检查显示白细胞增多和C反应蛋白水平升高。他的体征和症状提示支气管肺炎，遂开始抗菌治疗。痰涂片镜检发现革兰阴性球菌，培养结果显示为[此处原文缺失具体培养结果]，治疗后的后续细菌标本显示微生物数量减少。尽管患者有淀粉样变性和新冠病毒感染病史，但其临床病程仍取得了良好结果。[此处原文缺失具体感染名称]感染在一般健康个体中较为罕见，某些情况可能与病原体感染有关，否则主要见于免疫功能低下的宿主。在我们的病例中，淀粉样变性病史和近期的新冠病毒感染可能促成了脑膜炎球菌性支气管肺炎的发生。
