• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

静脉注射地诺前列酮成功治疗透明质酸诱导的面部坏死

Successful Treatment of Hyaluronic Acid-Induced Facial Necrosis With Intravenous Dinoprostone.

作者信息

Gaudissart Olivia, De Greef Axel, Fierens Hugues, Baeck Marie

机构信息

Department of Dermatology, Cliniques universitaires Saint-Luc (UCLouvain), Brussels, BEL.

Department of Dermatology, Clinique Saint-Jean, Brussels, BEL.

出版信息

Cureus. 2024 Sep 7;16(9):e68847. doi: 10.7759/cureus.68847. eCollection 2024 Sep.

DOI:10.7759/cureus.68847
PMID:39376876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11456907/
Abstract

There is an increasing interest in the use of facial dermal filler injections, such as hyaluronic acid, for esthetic and rejuvenation purposes. However, their use is associated with a potential risk of complications. We report the case of a woman in her thirties, with rapidly evolving facial skin necrosis following accidental intravascular injection of hyaluronic acid and/or extravascular compression. The necrosis worsened despite early repeated local injections of hyaluronidase. However, rapid and favorable clinical evolution was observed after the patient was treated for seven consecutive days with intravenous infusion of dinoprostone (a prostaglandin E2).

摘要

人们越来越关注使用面部真皮填充剂注射,如透明质酸,用于美容和年轻化目的。然而,它们的使用与潜在的并发症风险相关。我们报告了一例三十多岁女性的病例,该患者在意外血管内注射透明质酸和/或血管外压迫后,面部皮肤迅速出现坏死。尽管早期反复局部注射透明质酸酶,坏死仍加剧。然而,在患者连续七天接受静脉输注地诺前列酮(一种前列腺素E2)治疗后,观察到了快速且良好的临床进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4801/11456907/a570ec1d7fce/cureus-0016-00000068847-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4801/11456907/888b78799ee1/cureus-0016-00000068847-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4801/11456907/8f3dd7f41c26/cureus-0016-00000068847-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4801/11456907/a570ec1d7fce/cureus-0016-00000068847-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4801/11456907/888b78799ee1/cureus-0016-00000068847-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4801/11456907/8f3dd7f41c26/cureus-0016-00000068847-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4801/11456907/a570ec1d7fce/cureus-0016-00000068847-i03.jpg

相似文献

1
Successful Treatment of Hyaluronic Acid-Induced Facial Necrosis With Intravenous Dinoprostone.静脉注射地诺前列酮成功治疗透明质酸诱导的面部坏死
Cureus. 2024 Sep 7;16(9):e68847. doi: 10.7759/cureus.68847. eCollection 2024 Sep.
2
Clinical Outcomes of Impending Nasal Skin Necrosis Related to Nose and Nasolabial Fold Augmentation with Hyaluronic Acid Fillers.与使用透明质酸填充剂进行鼻部及鼻唇沟填充相关的即将发生的鼻皮肤坏死的临床结局
Plast Reconstr Surg. 2015 Oct;136(4):434e-441e. doi: 10.1097/PRS.0000000000001579.
3
Facial vascular danger zones for filler injections.面部血管危险区域填充注射。
Dermatol Ther. 2020 Nov;33(6):e14285. doi: 10.1111/dth.14285. Epub 2020 Sep 18.
4
Efficacy of Percutaneous Intraarterial Facial/Supratrochlear Arterial Hyaluronidase Injection for Treatment of Vascular Embolism Resulting From Hyaluronic Acid Filler Cosmetic Injection.经皮面动脉/滑车上动脉内注射透明质酸酶治疗透明质酸填充美容注射所致血管栓塞的疗效。
Aesthet Surg J. 2022 May 18;42(6):649-655. doi: 10.1093/asj/sjab425.
5
Complications of Injectables.注射剂的并发症。
Atlas Oral Maxillofac Surg Clin North Am. 2024 Mar;32(1):57-63. doi: 10.1016/j.cxom.2023.10.005. Epub 2023 Nov 24.
6
The "ART" of facial filler injections: Avoid, recognize, and treat hyaluronic acid-induced complications.面部填充剂注射的“艺术”:避免、识别和治疗透明质酸引起的并发症。
J Cosmet Dermatol. 2020 Sep;19(9):2229-2236. doi: 10.1111/jocd.13611. Epub 2020 Aug 2.
7
Management of vascular complications following facial hyaluronic acid injection: High-dose hyaluronidase protocol: A technical note.面部透明质酸注射后血管并发症的管理:大剂量透明质酸酶方案:技术说明。
J Stomatol Oral Maxillofac Surg. 2022 Apr;123(2):262-265. doi: 10.1016/j.jormas.2021.05.014. Epub 2021 Jun 19.
8
Cross-linked hyaluronic acid filler hydrolysis with hyaluronidase: Different settings to reproduce different clinical scenarios.透明质酸酶对交联透明质酸填充剂的水解作用:用于重现不同临床场景的不同设置
Dermatol Ther. 2020 Mar;33(2):e13269. doi: 10.1111/dth.13269. Epub 2020 Feb 25.
9
A Scoping Review of Hyaluronidase Use in Managing the Complications of Aesthetic Interventions.透明质酸酶在处理美容干预并发症中的应用:范围综述
Aesthetic Plast Surg. 2024 Mar;48(6):1193-1209. doi: 10.1007/s00266-022-03207-9. Epub 2022 Dec 19.
10
The Effect of Hyaluronidase on Depth of Necrosis in Hyaluronic Acid Filling-Related Skin Complications.透明质酸填充相关皮肤并发症中透明质酸酶对坏死深度的影响。
Aesthetic Plast Surg. 2020 Oct;44(5):1778-1785. doi: 10.1007/s00266-020-01759-2. Epub 2020 May 18.

本文引用的文献

1
Intra-arterial facial injection of hyaluronic acid complicated by Nicolau's dermatitis: Treatment with iloprost.动脉内注射透明质酸至面部并发尼科劳皮炎:用伊洛前列素治疗。
J Eur Acad Dermatol Venereol. 2023 Nov;37(11):e1314-e1315. doi: 10.1111/jdv.19304. Epub 2023 Jul 12.
2
Use of the high-dose pulsed hyaluronidase protocol in the management of impending skin necrosis associated with hyaluronic acid fillers: a systematic review.高剂量脉冲透明质酸酶方案在管理与透明质酸填充物相关的即将发生的皮肤坏死中的应用:系统评价。
Int J Oral Maxillofac Surg. 2023 Jan;52(1):79-87. doi: 10.1016/j.ijom.2022.07.006. Epub 2022 Aug 5.
3
Role of prostaglandin E2 in tissue repair and regeneration.
前列腺素 E2 在组织修复和再生中的作用。
Theranostics. 2021 Aug 13;11(18):8836-8854. doi: 10.7150/thno.63396. eCollection 2021.
4
Dermal Filler-Induced Vascular Occlusion Successfully Treated With Tadalafil, Hyaluronidase, and Aspirin.他达拉非、透明质酸酶和阿司匹林成功治疗填充剂所致的血管阻塞
Dermatol Surg. 2021 Aug 1;47(8):1160-1162. doi: 10.1097/DSS.0000000000002894.
5
Treatment Algorithm for Hyaluronic Acid-Related Complication Based on a Systematic Review of Case Reports, Case Series, and Clinical Experience.基于病例报告、病例系列和临床经验的系统评价制定的透明质酸相关并发症治疗算法
Craniomaxillofac Trauma Reconstr. 2020 Dec;13(4):313-328. doi: 10.1177/1943387520952687. Epub 2020 Sep 1.
6
Delayed skin necrosis following hyaluronic acid filler injection: A case report.透明质酸填充剂注射后延迟性皮肤坏死:一例报告。
J Cosmet Dermatol. 2020 Mar;19(3):582-584. doi: 10.1111/jocd.13287. Epub 2020 Jan 11.
7
This month's guideline: The Use of Hyaluronidase in Aesthetic Practice (v2.4).本月指南:透明质酸酶在美容实践中的应用(第2.4版)
J Clin Aesthet Dermatol. 2018 Jun;11(6):E61-E68. Epub 2018 Jun 1.
8
Nicolau syndrome due to hyaluronic acid injections.透明质酸注射所致的尼科劳综合征。
J Cosmet Laser Ther. 2016 Aug;18(4):239-44. doi: 10.3109/14764172.2016.1157260. Epub 2016 Apr 22.
9
Facial Filler Complications.面部填充剂并发症
Facial Plast Surg Clin North Am. 2015 Nov;23(4):447-58. doi: 10.1016/j.fsc.2015.07.006.
10
Treatment of Hyaluronic Acid Filler-Induced Impending Necrosis With Hyaluronidase: Consensus Recommendations.用透明质酸酶治疗透明质酸填充剂引起的即将发生的坏死:共识建议。
Aesthet Surg J. 2015 Sep;35(7):844-9. doi: 10.1093/asj/sjv018. Epub 2015 May 10.