Revúsová V, Zvara V, Karlíková L, Suchánek B
Czech Med. 1985;8(4):207-13.
In 78 patients with hypomagnesemia in urolithiasis the clinical course of disease was established in relation to therapy and dynamics of changes of serum magnesium levels. Almost 70% of patients had multiple, bilateral or recurrent nephrolithiasis or nephrocalcinosis. 70% of patients had Ca-oxalate stones or bilateral nephrocalcinosis. In 52% of patients a long-term magnesium supplementation was necessary. Significant progress of nephrolithiasis and nephrocalcinosis was observed in 80% of patients with permanent hypomagnesemia and in 4% of patients with normalization of serum magnesium level. Three of 15 patients with hypomagnesemia and progress of disease were transplanted a kidney and two were treated by hemodialysis. All five patients with renal failure had bilateral nephrocalcinosis, in three of them familiar occurrence of nephrolithiasis and hypomagnesemia was found.
在78例尿路结石合并低镁血症患者中，根据治疗情况及血清镁水平变化动态确定了疾病的临床病程。近70%的患者患有多发性、双侧性或复发性肾结石或肾钙质沉着症。70%的患者有草酸钙结石或双侧肾钙质沉着症。52%的患者需要长期补充镁。在80%的持续性低镁血症患者和4%血清镁水平恢复正常的患者中观察到肾结石和肾钙质沉着症有显著进展。15例低镁血症且疾病进展的患者中有3例接受了肾移植，2例接受了血液透析治疗。所有5例肾衰竭患者均有双侧肾钙质沉着症，其中3例有家族性肾结石和低镁血症病史。
