Nardini Marco, Chaudhuri Nilanjan, Lodhia Joshil, Milton Richard, Tcherveniakov Peter, Teh Elaine, Brunelli Alessandro
Department of Thoracic Surgery, St James's University Hospital, Leeds, UK.
School of Medicine, University of Leeds, Leeds, UK.
Interdiscip Cardiovasc Thorac Surg. 2025 Aug 5;40(8). doi: 10.1093/icvts/ivae172.
Our objective was to assess the incidence and reason of last-minute cancellations before surgery for lung cancer and their association with outcomes.
Retrospective analysis on all consecutive patients booked for elective lung cancer surgery from January 2017 through December 2022 in a single centre. Last-minute cancellation: a cancellation occurring within the last 24 h from the planned operation. Cancellation categories: process-related and patient-related. The short-term and long-term outcomes of patients who experienced a last-minute cancellation were analysed.
197 patients of 1587 (12%) had a last-minute cancellation: 156 (79%) were process-related and 41 (21%) were patient-related. Three percent (5/156) of patients cancelled for process reasons did not receive surgery versus 39% (16/41) of those cancelled for patient-related reasons, P < 0.0001. The 90-day mortality rates of cancelled and non-cancelled patients were similar (4.6% vs 4.7%, P = 1). Five-year overall survival of patients with cancellation was 58% (95% confidence interval 49-66) vs 69% (95% confidence interval 66-71) of those without cancellations, P = 0.022. Among those who had a cancellation, the 5-year overall survival of those with process-related cancellations was 61% (52-60) vs 35% (14-58) of those with patient-related cancellations (adjusted P value for multiple comparisons = 0.14). Cox regression analysis showed that surgery cancellations within the last 24 h for patient-related (hazard ratio 1.87, 95% confidence interval 1.02-3.42, P = 0.043) reasons remained a factor associated with poorer overall survival after adjusting for clinical stage, type of operation and patient-related variables.
Implementing the patient's preoperative clinical evaluation to reduce the occurrence of related last-minute cancellations might mitigate its negative impact on survival.
我们的目的是评估肺癌手术前最后一刻取消手术的发生率、原因及其与预后的关联。
对2017年1月至2022年12月在单一中心预定择期肺癌手术的所有连续患者进行回顾性分析。最后一刻取消手术:在计划手术前最后24小时内发生的取消。取消类别:与流程相关和与患者相关。分析经历最后一刻取消手术的患者的短期和长期预后。
1587例患者中有197例(12%)最后一刻取消手术:156例(79%)与流程相关,41例(21%)与患者相关。因流程原因取消手术的患者中有3%(5/156)未接受手术,而因患者相关原因取消手术的患者中有39%(16/41)未接受手术,P<0.0001。取消手术和未取消手术患者的90天死亡率相似(4.6%对4.7%,P=1)。取消手术患者的5年总生存率为58%(95%置信区间49-66),未取消手术患者为69%(95%置信区间66-71),P=0.022。在取消手术的患者中,与流程相关的取消手术患者的5年总生存率为61%(52-60),与患者相关的取消手术患者为35%(14-58)(多重比较校正P值=0.14)。Cox回归分析显示,在调整临床分期、手术类型和患者相关变量后,因患者相关原因在最后24小时内取消手术(风险比1.87,95%置信区间1.02-3.42,P=0.043)仍然是与总体生存率较差相关的一个因素。
实施患者术前临床评估以减少相关最后一刻取消手术的发生,可能会减轻其对生存的负面影响。