International Centre for Education and Research in Cardiovascular Pathology and Cardiovisualization, Samara State Medical University, 18 Gagarina Street, 443096 Samara, Russia,
Psychiatr Danub. 2024 Sep;36(Suppl 2):303-307.
To estimate quality of life (QoL) in patients with paroxysmal atrial fibrillation (AF) using the SF-36 Health Status Survey.
In a single-center study involving 6,630 patients, we defined a group of 97 patients having an incidental finding of atrial fibrillation (AF). The control group included 99 patients from the same primary cohort, but without paroxysmal AF. The two study groups matched closely in anthropometric parameters and comorbidity. All patients underwent standard laboratory and instrumental research methods. In the primary visit, at the time of AF detection, we evaluated the patients QoL using the classical SF-36 Health Status Survey. At the second visit (6±0.5 months follow-up) and third visit (12±0.5 months follow-up), we re-evaluated the QoL using the SF-36 Health Status Survey.
The absolute majority (95/97; 98%) of patients of the main group had a special variant of extrasystoles, namely the early atrial "P on T" type (versus 4.0% incidence in the control group) [OR 846 (382;187,000)]. The main group showed a significantly greater frequency of supraventricular extrasystoles. At the 1 visit, there was no group differences in QoL scores between the main and control groups (p>0.05). However, at 6 and 12 months follow-up, metrics of physical and mental health differed significantly between groups stratified by low and high QoL (p<0.05). The asymptomatic patients with paroxysmal AF and high compliance in oral anticoagulant therapy showed higher physical activity and social functioning.
Paroxysmal AF in asymptomatic patients is a predictor for declining QoL during 12 months follow-up in patients with cardiovascular pathology. The paroxysmal AF patients who had high compliance of oral anticoagulant therapy proved to have improved physical activity and social functioning.
使用 SF-36 健康状况调查评估阵发性心房颤动（AF）患者的生活质量（QoL）。
在一项涉及 6630 名患者的单中心研究中，我们定义了一组 97 名偶然发现心房颤动（AF）的患者。对照组包括来自同一初级队列的 99 名无阵发性 AF 的患者。两组在人体测量参数和合并症方面匹配良好。所有患者均接受了标准的实验室和仪器研究方法。在初次就诊时，即在发现 AF 时，我们使用经典的 SF-36 健康状况调查评估了患者的 QoL。在第二次就诊（6±0.5 个月随访）和第三次就诊（12±0.5 个月随访）时，我们使用 SF-36 健康状况调查重新评估了 QoL。
主要组中的绝大多数（95/97；98%）患者有一种特殊的早搏类型，即早期心房“P on T”型（对照组为 4.0%）[OR 846（382；187，000）]。主要组显示出更高频率的室上性早搏。在第 1 次就诊时，主要组和对照组之间的 QoL 评分没有组间差异（p>0.05）。然而，在 6 个月和 12 个月的随访中，根据 QoL 高低分层的两组之间的身心健康指标存在显著差异（p<0.05）。无症状阵发性 AF 且口服抗凝治疗依从性高的患者表现出更高的身体活动和社会功能。
无症状阵发性 AF 是心血管疾病患者 12 个月随访期间 QoL 下降的预测因素。口服抗凝治疗依从性高的阵发性 AF 患者表现出更高的身体活动和社会功能。
