Koning Stephanie M, Adam Emma K, Kapoor Amita, McDade Thomas W
University of Nevada, Reno, School of Public Health, 1664 N. Virginia Street, Reno, NV 89557, USA.
Northwestern University, USA.
Psychoneuroendocrinology. 2025 Jan;171:107189. doi: 10.1016/j.psyneuen.2024.107189. Epub 2024 Sep 21.
Armed conflict, displacement, and related violence is escalating globally, concentrated among civilians and migrants in border areas, and poses grave harms to women and children. The current study investigates how women's life-course experiences of conflict and displacement are linked to maternal stress and health outcomes after childbirth at the Thailand-Myanmar border, specifically stress, mental health, and cardiometabolic outcomes. Analyses are based on a cross-sectional population-based maternal and child health survey of 701 mothers, collected in 2017-18 in northern Thailand along the Myanmar border, including in camps, worksites, and residential homes. Results suggest that how conflict violence shapes contemporary stress and health depends on the outcome, level and timing of conflict violence exposure, and subsequent contextual threats and deprivation in displacement contexts. Past conflict violence was associated with symptoms of perceived stress (PS) and generalized anxiety disorder (GAD) but not depression. It was also associated with hypothalamic-pituitary-adrenal (HPA) axis activity (hair cortisol concentration) and adiposity (waist circumference and waist-to-hip ratio). Additionally, past conflict violence that began in childhood was particularly salient for PS, GAD, and adiposity; and level and timing of violence were salient jointly for HPA activity. Post-displacement factors also independently predicted higher blood pressure and played a potentially partial mediating role in the association between conflict exposure and both PS and GAD symptoms.
武装冲突、流离失所及相关暴力在全球范围内不断升级,集中于边境地区的平民和移民群体,对妇女和儿童造成了严重伤害。本研究调查了泰国-缅甸边境地区妇女在冲突和流离失所中的人生经历与产后母亲压力及健康结果之间的联系,具体涉及压力、心理健康和心脏代谢结果。分析基于2017 - 2018年在泰国北部沿缅甸边境对701名母亲进行的一项基于人群的横断面母婴健康调查,调查地点包括难民营、工作场所和住宅。结果表明,冲突暴力如何塑造当代压力和健康状况取决于冲突暴力暴露的结果、程度和时间,以及流离失所背景下随后出现的环境威胁和匮乏状况。过去的冲突暴力与感知压力(PS)症状和广泛性焦虑障碍(GAD)有关,但与抑郁症无关。它还与下丘脑-垂体-肾上腺(HPA)轴活动(头发皮质醇浓度)和肥胖(腰围和腰臀比)有关。此外,始于童年时期的过去冲突暴力对PS、GAD和肥胖的影响尤为显著;暴力的程度和时间对HPA活动有共同的显著影响。流离失所后的因素也独立预测了更高的血压,并在冲突暴露与PS和GAD症状之间的关联中发挥了潜在的部分中介作用。