Suppr超能文献

语义性痴呆是一种过时的实体吗?

Is semantic dementia an outdated entity?

机构信息

Service de neurologie, CMRR Haute Bretagne, CHU Pontchaillou, 35000 Rennes, France; Normandie Univ, UNICAEN, PSL Research University, EPHE, INSERM, U1077, CHU de Caen, Neuropsychologie et Imagerie de la Mémoire Humaine, 14000 Caen, France.

Service de neurologie, CMRR Haute Bretagne, CHU Pontchaillou, 35000 Rennes, France; Normandie Univ, UNICAEN, PSL Research University, EPHE, INSERM, U1077, CHU de Caen, Neuropsychologie et Imagerie de la Mémoire Humaine, 14000 Caen, France.

出版信息

Cortex. 2024 Nov;180:64-77. doi: 10.1016/j.cortex.2024.09.002. Epub 2024 Sep 17.

Abstract

Does it still make clinical sense to talk about semantic dementia? For more than 10 years, some researchers and clinicians have highlighted the need for new diagnostic criteria, arguing for this entity either to be redefined or, more recently, to be divided into two partially distinct entities, each with its own supposed characteristics, namely the semantic variant primary progressive aphasia and the semantic behavioral variant frontotemporal dementia. Why such a shift? Is it no longer appropriate to talk about semantic dementia? Is it really useful to divide the concept of semantic dementia into verbal and socioemotional semantic subcomponents? Does this proposal have any clinical merit or does it solely reflect theoretical considerations? To shed light on these questions, the purpose of the present review was to explore theoretical considerations on the nature of the knowledge that is disturbed in this disease which might justify such terminological changes.

摘要

谈到语义性痴呆,它在临床上还有意义吗? 10 多年来,一些研究人员和临床医生强调需要新的诊断标准,主张重新定义该实体,或者最近将其分为两个部分不同的实体,每个实体都有其自身的特征,即语义变异原发性进行性失语症和语义行为变异额颞叶痴呆症。为什么会有这样的转变?语义性痴呆症的说法不再合适了吗?将语义性痴呆症的概念分为言语和社会情感语义亚成分真的有用吗?这个提议有任何临床意义,还是仅仅反映了理论考虑?为了阐明这些问题,本综述的目的是探讨对这种疾病中受干扰的知识性质的理论考虑,这些考虑可能证明这种术语变化是合理的。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验