Service de neurologie, CMRR Haute Bretagne, CHU Pontchaillou, 35000 Rennes, France; Normandie Univ, UNICAEN, PSL Research University, EPHE, INSERM, U1077, CHU de Caen, Neuropsychologie et Imagerie de la Mémoire Humaine, 14000 Caen, France.
Service de neurologie, CMRR Haute Bretagne, CHU Pontchaillou, 35000 Rennes, France; Normandie Univ, UNICAEN, PSL Research University, EPHE, INSERM, U1077, CHU de Caen, Neuropsychologie et Imagerie de la Mémoire Humaine, 14000 Caen, France.
Cortex. 2024 Nov;180:64-77. doi: 10.1016/j.cortex.2024.09.002. Epub 2024 Sep 17.
Does it still make clinical sense to talk about semantic dementia? For more than 10 years, some researchers and clinicians have highlighted the need for new diagnostic criteria, arguing for this entity either to be redefined or, more recently, to be divided into two partially distinct entities, each with its own supposed characteristics, namely the semantic variant primary progressive aphasia and the semantic behavioral variant frontotemporal dementia. Why such a shift? Is it no longer appropriate to talk about semantic dementia? Is it really useful to divide the concept of semantic dementia into verbal and socioemotional semantic subcomponents? Does this proposal have any clinical merit or does it solely reflect theoretical considerations? To shed light on these questions, the purpose of the present review was to explore theoretical considerations on the nature of the knowledge that is disturbed in this disease which might justify such terminological changes.
谈到语义性痴呆,它在临床上还有意义吗? 10 多年来,一些研究人员和临床医生强调需要新的诊断标准,主张重新定义该实体,或者最近将其分为两个部分不同的实体,每个实体都有其自身的特征,即语义变异原发性进行性失语症和语义行为变异额颞叶痴呆症。为什么会有这样的转变?语义性痴呆症的说法不再合适了吗?将语义性痴呆症的概念分为言语和社会情感语义亚成分真的有用吗?这个提议有任何临床意义,还是仅仅反映了理论考虑?为了阐明这些问题,本综述的目的是探讨对这种疾病中受干扰的知识性质的理论考虑,这些考虑可能证明这种术语变化是合理的。