Kuang Dai, Liu Wei, Chen Daohu, Jiang Jingsi, Wang Yi, Xia Qianfeng
NHC Key Laboratory of Tropical Disease Control, School of Tropical Medicine, Hainan Medical University, Haikou, China.
The Second Affiliated Hospital of Hainan Medical University, Haikou, China.
Am J Trop Med Hyg. 2024 Oct 8;111(6):1252-1255. doi: 10.4269/ajtmh.24-0237. Print 2024 Dec 4.
Burkholderia pseudomallei is a Gram-negative bacterium found predominantly in tropical and subtropical regions. A 49-year-old individual with type 2 diabetes in Hainan, China, with a 4-month history of intermittent fever and 20 days of chest-back pain was diagnosed with aortic pseudoaneurysm through a computerized tomography scan. Burkholderia pseudomallei was identified through bacteriological examination of the patient's blood. The patient received supportive care, with management of hyperthermia, heart rate, blood pressure, and blood glucose levels. Intravenous meropenem and oral sulfamethoxazole were administered for anti-infection treatment. Within 10 days, the patient's temperature normalized, vital signs stabilized, chest pain subsided, and blood cultures cleared. This case highlights the potential severity of B. pseudomallei infections, underscoring the critical role of appropriate antibiotics, supportive care, and long-term follow-up in ensuring comprehensive management and preventing further transmission.
类鼻疽伯克霍尔德菌是一种革兰氏阴性菌，主要存在于热带和亚热带地区。中国海南一名49岁的2型糖尿病患者，有4个月间歇性发热病史及20天胸背部疼痛，通过计算机断层扫描诊断为主动脉假性动脉瘤。通过对患者血液进行细菌学检查鉴定出类鼻疽伯克霍尔德菌。患者接受了支持治疗，包括对体温、心率、血压和血糖水平的管理。静脉注射美罗培南和口服磺胺甲恶唑进行抗感染治疗。10天内，患者体温恢复正常，生命体征稳定，胸痛缓解，血培养转阴。该病例突出了类鼻疽伯克霍尔德菌感染的潜在严重性，强调了适当抗生素、支持治疗及长期随访在确保综合管理和预防进一步传播方面所起 的关键作用。
