Kawaguchi Kengo, Endo Makoto, Sagiyama Koji, Maekawa Akira, Nabeshima Akira, Fujiwara Toshifumi, Oda Yoshinao, Nakashima Yasuharu
Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-Ku, Fukuoka, Japan.
Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-Ku, Fukuoka, Japan.
Skeletal Radiol. 2025 Jun;54(6):1341-1346. doi: 10.1007/s00256-024-04811-3. Epub 2024 Oct 8.
Synovial chondrosarcoma (CHS) is a rare malignant tumor arising from the synovial tissue and is often associated with synovial chondromatosis. Herein, we present a unique case of primary synovial CHS in the shoulder joint without evidence of synovial chondromatosis. A 60-year-old man presented to our hospital with a complain of left shoulder pain that persisted for 6 years, which was initially misdiagnosed as synovitis. Radiography revealed an osteolytic lesion involving the humerus and the scapula. Histologically, the tumor exhibited features of grade 2 synovial CHS, infiltrating the trabecular bones and intra-articular space. Wide resection led to a 9-year recurrence-free survival. This case underscores the challenges in diagnosing and managing synovial CHS, particularly in cases with atypical presentations lacking synovial chondromatosis, necessitating careful follow-up and adequate surgical intervention.
滑膜软骨肉瘤（CHS）是一种起源于滑膜组织的罕见恶性肿瘤，常与滑膜软骨瘤病相关。在此，我们报告一例独特的肩关节原发性滑膜CHS病例，无滑膜软骨瘤病证据。一名60岁男性因左肩疼痛持续6年就诊于我院，最初被误诊为滑膜炎。影像学检查显示肱骨和肩胛骨有溶骨性病变。组织学上，肿瘤表现为2级滑膜CHS特征，浸润小梁骨和关节内间隙。广泛切除导致9年无复发生存期。该病例强调了诊断和管理滑膜CHS的挑战，特别是在缺乏滑膜软骨瘤病的非典型表现病例中，需要仔细随访和充分的手术干预。
