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小叶型乳腺癌子宫转移:一例报告

Uterine Metastasis From Lobular Breast Carcinoma: A Case Report.

作者信息

Faraz Aniqa, Kowalczyk Sydni, Hendrixson Mark

机构信息

Internal Medicine, Cumberland Medical Center, Crossville, USA.

Oncology, Lincoln Memorial University DeBusk College of Osteopathic Medicine, Harrogate, USA.

出版信息

Cureus. 2024 Sep 8;16(9):e68943. doi: 10.7759/cureus.68943. eCollection 2024 Sep.

DOI:10.7759/cureus.68943
PMID:39381447
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11460646/
Abstract

There have been a few reports of extra pelvic tumors migrating into the female genital tract. Patients with postmenopausal vaginal bleeding are typically suspected of having primary uterine cancer. We present a case of lobular breast cancer that manifested about two years later as an atypical vaginal bleeding and was found to have endometrial and myometrial metastases. Pathological evaluation of endometrial and endocervical tissue samples revealed that breast cancer was the underlying cause.

摘要

已有一些关于盆腔外肿瘤转移至女性生殖道的报道。绝经后阴道出血的患者通常怀疑患有原发性子宫癌。我们报告一例小叶性乳腺癌病例,约两年后表现为非典型阴道出血,发现有子宫内膜和肌层转移。子宫内膜和宫颈组织样本的病理评估显示,乳腺癌是根本病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4578/11460646/c6c9299f38da/cureus-0016-00000068943-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4578/11460646/b2e4ba92a20f/cureus-0016-00000068943-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4578/11460646/c998ac9c7085/cureus-0016-00000068943-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4578/11460646/7b12eee3e7a5/cureus-0016-00000068943-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4578/11460646/2fee100b7227/cureus-0016-00000068943-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4578/11460646/c6c9299f38da/cureus-0016-00000068943-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4578/11460646/b2e4ba92a20f/cureus-0016-00000068943-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4578/11460646/c998ac9c7085/cureus-0016-00000068943-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4578/11460646/7b12eee3e7a5/cureus-0016-00000068943-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4578/11460646/2fee100b7227/cureus-0016-00000068943-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4578/11460646/c6c9299f38da/cureus-0016-00000068943-i05.jpg

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In Vivo. 2025 Jul-Aug;39(4):2456-2463. doi: 10.21873/invivo.14046.

本文引用的文献

1
Uterine Metastasis Presenting as Abnormal Uterine Bleeding in a Case of Primary Breast Cancer Identified on F-FDG PET/CT.原发性乳腺癌 F-FDG PET/CT 检查中发现的以异常子宫出血为表现的子宫转移。
J Nucl Med Technol. 2023 Dec 5;51(4):333-334. doi: 10.2967/jnmt.123.266221.
2
Asymptomatic uterine metastasis of breast cancer: Case report and literature review.乳腺癌无症状性子宫转移:病例报告及文献复习。
Medicine (Baltimore). 2022 Oct 14;101(41):e31061. doi: 10.1097/MD.0000000000031061.
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Breast Cancer Metastasis: Mechanisms and Therapeutic Implications.
乳腺癌转移:机制与治疗意义。
Int J Mol Sci. 2022 Jun 18;23(12):6806. doi: 10.3390/ijms23126806.
4
Lobular carcinoma of the breast with metastasis to the uterine cervix.乳腺小叶癌伴宫颈转移。
J Cancer Res Ther. 2019 Oct-Dec;15(6):1411-1414. doi: 10.4103/jcrt.JCRT_469_18.
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Lobular breast cancer metastasis to uterus during adjuvant tamoxifen treatment: A case report and review of the literature.小叶性乳腺癌在辅助他莫昔芬治疗期间转移至子宫:一例病例报告及文献复习
J Cancer Res Ther. 2018 Jul-Sep;14(5):1135-1137. doi: 10.4103/0973-1482.187235.
6
Endometrial Metastasis from Ductal Breast Carcinoma: A Case Report with Literature Review.导管原位癌子宫内膜转移:一例报告并文献复习
Am J Case Rep. 2018 Apr 27;19:494-499. doi: 10.12659/AJCR.907638.
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Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics.乳腺浸润性小叶癌:形态学、生物标志物与“组学”
Breast Cancer Res. 2015 Jan 30;17(1):12. doi: 10.1186/s13058-015-0519-x.
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Breast cancer with synchronous massive metastasis in the uterine cervix: a case report and review of the literature.乳腺癌伴宫颈同步巨大转移:病例报告及文献复习。
Arch Gynecol Obstet. 2010 Apr;281(4):769-73. doi: 10.1007/s00404-009-1264-0. Epub 2009 Oct 30.
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Metastases to the uterine corpus from extragenital cancers. A clinicopathologic study of 63 cases.生殖器外癌症转移至子宫体。63例临床病理研究。
Cancer. 1982 Nov 15;50(10):2163-9. doi: 10.1002/1097-0142(19821115)50:10<2163::aid-cncr2820501032>3.0.co;2-f.