Martinez G, Ferreira R, Colombo B
Acta Haematol. 1985;74(3):186-8. doi: 10.1159/000206208.
The inheritance of the alpha-chain hemoglobin variant G Philadelphia was studied in three Cuban families of African ancestry. The variant represented approximately 33% of the total adult hemoglobin in all subjects, and was associated to a 10.5 kb Bam HI restriction fragment. Mild hematological alterations were present. These data indicate that also in the Cuban population the alpha G Philadelphia locus is linked to a deletional alpha-thalassemia.
在三个具有非洲血统的古巴家庭中研究了α链血红蛋白变体G费城的遗传情况。该变体在所有受试者的成人血红蛋白总量中约占33%，并与一个10.5 kb的Bam HI限制性片段相关。存在轻度血液学改变。这些数据表明，在古巴人群中，αG费城位点也与缺失型α地中海贫血相关。
