Baumbach Philipp, Storch Peter, Weiss Thomas, Meissner Winfried, Rottstädt Fabian
Universitätsklinikum Jena, Klinik für Anästhesiologie und Intensivmedizin, Friedrich-Schiller-Universität Jena, Am Klinikum 1, 07747, Jena, Deutschland.
Universitätsklinikum Jena, Klinik für Neurologie, Friedrich-Schiller-Universität Jena, Jena, Deutschland.
Schmerz. 2024 Oct 9. doi: 10.1007/s00482-024-00838-6.
Interdisciplinary multimodal pain therapy (IMPT) is an established treatment for patients with severe chronic pain. Little evidence is available on the role of treatment dosage and, in particular, on the association between the duration of IMPT and treatment outcome.
The aim of this retrospective study was to compare the medium-term treatment success of a short inpatient (SIT, 1 week) and a long outpatient (LOT, 4 weeks) IMPT with a comparable treatment concept and comparable therapy intensity (20 h/week) in patients with severe chronic pain.
Patients in both groups completed the German Pain Questionnaire at the beginning and end of IMPT as well as after 3 months. Primary outcome measures included pain-related impairment and average pain intensity at follow-up in patients of comparable sex, age as well as pain intensity and impairment at the beginning of the therapy.
While both groups initially showed significant treatment effects in pain-related impairment and average pain intensity, LOT patients (n = 32) reported significantly better values in both variables at 3‑month follow-up compared with SIT patients (n = 32). This was due to sustained positive effects in LOT patients and worsening in the SIT group.
The results indicate that initial treatment effects can be observed in both treatment settings, but a longer duration of therapy seems to favour the long-term stability of treatment effects.
跨学科多模式疼痛治疗(IMPT)是一种针对重度慢性疼痛患者的既定治疗方法。关于治疗剂量的作用,尤其是关于IMPT持续时间与治疗效果之间的关联,目前证据较少。
这项回顾性研究的目的是比较短期住院(SIT,1周)和长期门诊(LOT,4周)IMPT在重度慢性疼痛患者中的中期治疗成功率,这两种治疗具有可比的治疗理念和可比的治疗强度(每周20小时)。
两组患者在IMPT开始和结束时以及3个月后均完成了德国疼痛问卷。主要结局指标包括在随访时,具有可比性的性别、年龄、治疗开始时的疼痛强度和损伤程度的患者的疼痛相关损伤和平均疼痛强度。
虽然两组在疼痛相关损伤和平均疼痛强度方面最初均显示出显著的治疗效果,但与短期住院患者(n = 32)相比,长期门诊患者(n = 32)在3个月随访时在这两个变量上的报告值均显著更好。这是由于长期门诊患者的积极效果持续存在,而短期住院组的情况恶化。
结果表明,在两种治疗环境中均可观察到初始治疗效果,但较长的治疗持续时间似乎有利于治疗效果的长期稳定性。