（±）-茴芹根素的全合成
Total Synthesis of (±)-Anigorootin.
作者信息
Cano Marisol, Otálvaro Felipe
机构信息
Instituto de Química, Síntesis y Biosíntesis de Metabolitos Naturales, Universidad de Antioquia, AA 1226 Medellín, Colombia.
出版信息
Org Lett. 2024 Oct 18;26(41):8752-8755. doi: 10.1021/acs.orglett.4c03090. Epub 2024 Oct 9.
PMID:39382959
Abstract
An 11-step synthesis of the octacyclic-fused dimeric phenylphenalenone anigorootin (phytoalexin in banana plants) is reported. The synthetic strategy uses an electrochemical dimerization as the key step, which stereospecifically installs the four asymmetric centers. Mechanistic aspects of the dimerization process are discussed.
摘要
报道了八环稠合二聚体苯基苯并菲酮类抗根素（香蕉植物中的植物抗毒素）的11步合成。该合成策略以电化学二聚化为关键步骤，该步骤立体专一性地构建了四个不对称中心。讨论了二聚化过程的机理。
Zotero 插件