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用于监测运动员汗液生物标志物的柔性表皮可穿戴传感器。

Flexible epidermal wearable sensor for Athlete's sweat biomarkers monitoring.

作者信息

Cai Jian, Cao Mengzhu, Bai Jing, Sun Mimi, Ma Chongbo, Emran Mohammed Y, Kotb Ahmed, Bo Xiangjie, Zhou Ming

机构信息

Key Laboratory of Polyoxometalate and Reticular Material Chemistry of Ministry of Education, Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Analysis and Testing Center, Department of Chemistry, Northeast Normal University, Changchun, Jilin Province, 130024, China.

Chemistry Department, Faculty of Science, Al-Azhar University, Assiut, 71524, Egypt.

出版信息

Talanta. 2025 Jan 1;282:126986. doi: 10.1016/j.talanta.2024.126986. Epub 2024 Oct 4.

DOI:10.1016/j.talanta.2024.126986
PMID:39383716
Abstract

Wearable sweat sensors hold great promise for the monitoring of athletic sweat biomarkers that are reflective of physical status and the inimitable feature of wearable sensors to conduct dynamic sweat analysis in situ. However, the preparative methods of wearable patches for monitoring athlete's biomarkers are often complicated. Here, we demonstrate the first example of "sports lab-on-skin" as a fully integrated epidermal sweat sensor through simple laser engraving and laser cutting methods, which enables on-body and wirelessly measuring sweat Na, sweat K, sweat lactate, and initial sweat rate for physical status assessment. We test the performance of the "sports lab-on-skin" in both physically trained and un-trained groups under the same exercise intensity. We also validate the influence of different scenarios (water intake, breakfast, and exercise intensity) on dehydration time, sweat K level, sweat lactate level, and initial sweat rate.

摘要

可穿戴汗液传感器在监测反映身体状况的运动汗液生物标志物以及可穿戴传感器进行原位动态汗液分析的独特功能方面具有巨大潜力。然而,用于监测运动员生物标志物的可穿戴贴片的制备方法通常很复杂。在此,我们展示了首个通过简单的激光雕刻和激光切割方法制成的“运动皮肤实验室”,它是一种完全集成的表皮汗液传感器,能够在身体上无线测量汗液中的钠、钾、乳酸以及初始汗液速率,以评估身体状况。我们在相同运动强度下,对受过体育训练和未受过训练的两组人群测试了“运动皮肤实验室”的性能。我们还验证了不同场景(饮水、早餐和运动强度)对脱水时间、汗液钾水平、汗液乳酸水平和初始汗液速率的影响。

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