Busse William W
Division of Allergy, Pulmonary and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Ann Allergy Asthma Immunol. 2025 Jan;134(1):19-30. doi: 10.1016/j.anai.2024.09.021. Epub 2024 Oct 9.
Asthma remissions have been identified as a new treatment outcome and as based on experience with biologics. Remissions are defined as no symptoms, no exacerbations, no use of systemic corticosteroids, and stabilization (optimization) of lung functions; all these criteria need to be sustained for at least 1 year. This study discussed the evolution of remissions, the evolving criteria, and experiences in achieving remission after treatment with biologics. In severe, uncontrolled asthma, treatment with biologics has led to remissions in 20% to 35% of the subjects treated. It is proposed that remissions will become a new and important treatment outcome for asthma.
哮喘缓解已被确定为一种新的治疗结果，且基于生物制剂的应用经验。缓解被定义为无症状、无急性加重、未使用全身糖皮质激素以及肺功能稳定（优化）；所有这些标准需持续至少1年。本研究讨论了缓解的演变、不断变化的标准以及使用生物制剂治疗后实现缓解的经验。在重度、未控制的哮喘中，生物制剂治疗使20%至35%的治疗对象实现了缓解。有人提出，缓解将成为哮喘一种新的重要治疗结果。
