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面部皮肤结核感染非结核分枝杆菌。

Facial cutaneous tuberculosis infected by non-tuberculous mycobacteria.

机构信息

Department of ultrasonography, Hangzhou Red Cross Hospital, 208 Huan Cheng Dong Road, Gongshu District, Hangzhou, 310003, Zhejiang Province, China.

出版信息

BMC Infect Dis. 2024 Oct 9;24(1):1131. doi: 10.1186/s12879-024-10020-z.

Abstract

BACKGROUND

Cutaneous infections caused by non-tuberculous mycobacteria (NTM) are extremely rare, particularly when they are localized to the facial area. This condition presents significant diagnostic challenges due to its unusual presentation and the need for precise microbiological identification.

CASE PRESENTATION

A two-year-old male patient presented with a progressively enlarging reddish-brown mass on the left side of his face. Despite the absence of systemic symptoms, the lesion's growth warranted investigation due to its growth. Ultrasonography showed a hypoechoic mass in the dermis, indicating an underlying abscess. The subsequent aspiration resulted in pale yellow pus, which upon testing and culture, confirmed the presence of Mycobacterium avium complex infection, a species of NTM. This case exemplifies the synergy between imaging modalities and microbiological analysis, highlighting the crucial role of both in achieving favorable clinical outcomes in patients with suspected cutaneous NTM infections. Ultrasound can expedite diagnosis, improve treatment planning, and enhance patient care by enabling targeted interventions and monitoring response to therapy in these scenarios. However, it is the combination of pathogen-specific diagnostics that ensures accurate etiological attribution and appropriate antimicrobial stewardship.

CONCLUSION

Although rare, facial cutaneous infections caused by NTM still deserve thorough investigation to determine the exact cause. Ultrasound is used to identify cutaneous lesions, measure their extent, and guide surgical procedures. The ultimate diagnosis is based on microbiological confirmation.

摘要

背景

非结核分枝杆菌(NTM)引起的皮肤感染极为罕见,尤其是当它们局限于面部区域时。由于其不常见的表现形式和对精确微生物鉴定的需求,这种情况带来了重大的诊断挑战。

病例介绍

一名两岁男性患者左侧面部出现逐渐增大的红棕色肿块。尽管没有全身症状,但由于病变的生长,需要进行调查。超声检查显示真皮内低回声肿块,提示存在脓肿。随后的抽吸产生了淡黄色脓液,经检测和培养证实存在鸟分枝杆菌复合群感染,这是一种 NTM。该病例体现了影像学和微生物学分析之间的协同作用,突出了两者在疑似皮肤 NTM 感染患者中实现良好临床结果的关键作用。超声可以通过靶向干预和监测治疗反应来加速诊断、改善治疗计划并提高患者护理水平。然而,只有结合特定病原体的诊断才能确保准确的病因归因和适当的抗菌药物管理。

结论

尽管罕见,但仍需要彻底调查面部皮肤 NTM 感染以确定确切原因。超声用于识别皮肤病变、测量其范围并指导手术程序。最终诊断基于微生物学确认。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aad1/11465486/a68e6a0bbcdf/12879_2024_10020_Fig1_HTML.jpg

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