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不完全川崎病患者的阴囊和阴茎水肿:病例报告及文献复习。

Scrotal and penile edema in a patient with incomplete kawasaki disease: a case report and brief literature review.

机构信息

Wayne State University School of Medicine, 540 E Canfield Street, Detroit, MI, 48201, USA.

Department of Pediatric Infectious Disease, Children's Hospital of Michigan, 3901 Beaubien Blvd, Detroit, MI, 48201, USA.

出版信息

BMC Pediatr. 2024 Oct 9;24(1):640. doi: 10.1186/s12887-024-05099-x.

Abstract

BACKGROUND

Kawasaki disease (KD) is a medium artery vasculitis that predominantly affects children under age 5. Prompt diagnosis and treatment with IVIG and moderate dose aspirin is required to prevent the formation of coronary artery aneurysms. While scrotal edema and erythema have been seen in KD, here we present a distinctive case of incomplete Kawasaki with these features as well as penile edema.

CASE PRESENTATION

A 2-year-old, unvaccinated, African American male presented with 4 days of fever, bilateral limbic sparing conjunctivitis, a papular rash, unilateral shotty cervical lymphadenopathy, mild right-hand edema, and scrotal and penile edema and erythema. His labs were significant for sterile pyuria, elevated ALT, anemia for age, and hypoalbuminemia. He was diagnosed with incomplete Kawasaki disease and was treated with IVIG and moderate dose aspirin. Echocardiogram was negative for coronary aneurysms. His symptoms resolved and he was discharged home with low dose aspirin. At his 2-week follow up, he remained well-appearing with no refractory Kawasaki symptoms.

CONCLUSION

This is a unique case of penile edema in KD which to our knowledge has not been previously reported in literature. An understanding of genitourinary symptoms in Kawasaki disease can help timely diagnosis and treatment of the disease.

摘要

背景

川崎病(KD)是一种主要影响 5 岁以下儿童的中等动脉血管炎。需要及时诊断和治疗,使用静脉注射免疫球蛋白(IVIG)和中等剂量阿司匹林,以预防冠状动脉瘤的形成。虽然在川崎病中已经观察到阴囊水肿和红斑,但这里我们报告了一个独特的不完全川崎病病例,具有这些特征以及阴茎水肿。

病例介绍

一名 2 岁、未接种疫苗的非裔美国男性,发热 4 天,双侧边缘性眼结合膜炎,斑丘疹,单侧散在颈部淋巴结病,轻度右手水肿,阴囊和阴茎水肿和红斑。他的实验室检查结果显著为无菌性脓尿、ALT 升高、贫血和低白蛋白血症。他被诊断为不完全川崎病,并接受 IVIG 和中等剂量阿司匹林治疗。超声心动图未发现冠状动脉瘤。他的症状缓解并出院,在家中服用低剂量阿司匹林。在他 2 周的随访中,他表现良好,没有难治性川崎病症状。

结论

这是一个独特的川崎病阴茎水肿病例,据我们所知,文献中尚未报道过。了解川崎病的泌尿生殖系统症状有助于及时诊断和治疗该病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a5/11462718/75db2f3d54d6/12887_2024_5099_Fig1_HTML.jpg

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