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Impact of the Prognostic Nutritional Index on the Development of Sialocele or Salivary Fistula, After Parotidectomy.

作者信息

Paksoy Zehra Betül, Kundi Fatma Cemre Sazak

机构信息

Ankara City Hospital, Otorhinolaryngology, Ankara, Turkey.

Ankara Yıldırım Beyazıt University, Faculty of Medicine, Ankara, Turkey.

出版信息

Clin Otolaryngol. 2025 Jan;50(1):107-112. doi: 10.1111/coa.14244. Epub 2024 Oct 10.

Abstract

PURPOSE

Sialocele or salivary fistula formation is common after parotidectomy. This study aims to evaluate the predictive value of the prognostic nutritional index in the development of salivary fistulas and sialoceles after parotidectomy.

METHODS

Patients who underwent parotidectomy at our clinic and were diagnosed with benign salivary gland masses were included in the study. Patients who developed postoperative sialoceles or salivary fistulas were identified. Various factors were assessed, including surgical technique, tumour size, gender, age, prognostic nutritional index, and the volume of the excised mass. Variables associated with sialocele or salivary fistula were later included in a multiple logistic regression model. Possible factors related to the formation of sialocele or salivary fistulas were analysed.

RESULTS

The study comprised 158 patients (95 male and 63 female). The frequency of sialocele or salivary fistula development was 13.9% (n = 22). The multiple logistic regression model found that the prognostic nutritional index(PNI) was linked to the occurrence of sialocele or salivary fistula (ORs = 0.9, 95% CI = [0.9], p = 0.003). Warthin tumour was associated with an elevated risk of sialocele or salivary fistula (ORs = 0.38, 95% CI = [0.184, 0.79], p = 0.009). ROC analysis demonstrated that the PNI had a specificity of 90% and a sensitivity of 68%. No significant associations were observed between the excised tumour size, surgical technique with the development of sialocele or salivary fistula.

CONCLUSION

Prognostic nutritional index can be utilised as an independent risk factor for the development of sialocele, or salivary fistula.

摘要

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