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带布朗氏空肠吻合术的胰腺空肠吻合术式:100例胰十二指肠切除术的围手术期结果

Dunking Pancreaticojejunostomy With Braun's Jejunojejunostomy: Perioperative Outcomes of a Hundred Pancreaticoduodenectomies.

作者信息

Pandey Sampanna, Maharjan Narendra, Pradhan Sumita, Bhandari Ramesh S

机构信息

Department of Surgical Gastroenterology, Tribhuvan University Teaching Hospital, Maharajgunj Medical Campus, Institute of Medicine, Kathmandu, NPL.

出版信息

Cureus. 2024 Sep 9;16(9):e68988. doi: 10.7759/cureus.68988. eCollection 2024 Sep.

Abstract

Background The optimal surgical technique for pancreaticojejunostomy (PJ) following pancreaticoduodenectomy (PD) is still debated. Dunking and duct-to-mucosa PJ are the most commonly adopted techniques. Incorporating Braun's jejunojejunostomy (JJ) could reduce the incidence and severity of delayed gastric emptying (DGE). This retrospective descriptive study seeks to clarify the outcomes of dunking PJ with Braun's JJ in 100 PD patients. Methodology We retrospectively reviewed 100 patients who underwent PDs in a single unit of the Department of Surgical Gastroenterology of Tribhuvan University Teaching Hospital from October 2012 to February 2023. Demographic and historical data, indications, procedure-related data, complications, and mortality data were collected and analyzed. Results The mean age was 50.96 ± 14.97 years, and 64 (64%) were males. The most common indication was ampullary carcinoma (53, 53%) followed by distal cholangiocarcinoma (18, 18%) and pancreatic ductal adenocarcinoma (7, 7%). Operative time was 5.83 ± 1.09 hours, intraoperative blood loss was 515 ± 194 mL, and the average time for PJ and Braun's JJ was 22 ± 6 and 15 ± 3 minutes, respectively. Soft pancreas was encountered in 52 (52%) patients and clinically significant postoperative pancreatic fistula (Grade B, C) was seen in 23 (23%). Postpancreatectomy hemorrhage was seen in 21 (21%) patients (Grades A: 3, B: 12, C: 6). DGE (Grade B) occurred in two (2%) patients, and bile leak was observed in 4% of patients (Grades A: 1, B: 2, C: 1). Major complications (Clavien-Dindo ≥IIIA) occurred in 24%, and 11 patients died. Conclusions The dunking technique is easily adaptable, less time-consuming, and can be performed in the pancreas of any texture or duct size but is associated with an increased incidence of post-pancreatectomy hemorrhage. Incorporation of Braun's anastomosis lowers DGE, allows early initiation of feeding, and reduces complication rates.

摘要

背景

胰十二指肠切除术(PD)后胰肠吻合术(PJ)的最佳手术技术仍存在争议。套入式和导管对黏膜的PJ是最常用的技术。加做布朗氏空肠吻合术(JJ)可降低延迟性胃排空(DGE)的发生率和严重程度。这项回顾性描述性研究旨在阐明100例接受PD手术患者采用套入式PJ加布朗氏JJ的手术结果。

方法

我们回顾性分析了2012年10月至2023年2月在特里布万大学教学医院外科胃肠病科同一科室接受PD手术的100例患者。收集并分析了人口统计学和病史数据、手术指征、手术相关数据、并发症及死亡率数据。

结果

平均年龄为50.96±14.97岁,男性64例(64%)。最常见的手术指征是壶腹癌(53例,53%),其次是远端胆管癌(18例,18%)和胰腺导管腺癌(7例,7%)。手术时间为5.83±1.09小时,术中出血量为515±194毫升,PJ和布朗氏JJ的平均操作时间分别为22±6分钟和15±3分钟。52例(52%)患者胰腺质地柔软,23例(23%)患者出现具有临床意义的术后胰瘘(B级、C级)。21例(21%)患者发生胰切除术后出血(A级:3例,B级:12例,C级:6例)。2例(2%)患者发生DGE(B级),4%的患者出现胆漏(A级:1例,B级:2例,C级:1例)。严重并发症(Clavien-Dindo≥IIIA级)发生率为24%,11例患者死亡。

结论

套入式技术易于操作,耗时较短,可在任何质地或导管大小的胰腺上进行,但胰切除术后出血的发生率较高。加做布朗氏吻合术可降低DGE,允许早期开始进食,并降低并发症发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0dc/11463102/85059a63580a/cureus-0016-00000068988-i01.jpg

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