Cao Siyang, Wei Yihao, Yue Yaohang, Wang Deli, Yang Jun, Xiong Ao, Zeng Hui
National and Local Joint Engineering Research Centre of Orthopaedic Biomaterials, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Shenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Front Pharmacol. 2024 Sep 25;15:1477938. doi: 10.3389/fphar.2024.1477938. eCollection 2024.
Notable progress has been made in "ferroptosis-based nano drug delivery systems (NDDSs)" over the past 11 years. Despite the ongoing absence of a comprehensive scientometric overview and up-to-date scientific mapping research, especially regarding the evolution, critical research pathways, current research landscape, central investigative themes, and future directions.
Data ranging from 1 January 2012, to 30 November 2023, were obtained from the Web of Science database. A variety of advanced analytical tools were employed for detailed scientometric and visual analyses.
The results show that China significantly led the field, contributing 82.09% of the total publications, thereby largely shaping the research domain. Chen Yu emerged as the most productive author in this field. Notably, the journal had the greatest number of relevant publications. The study identified liver neoplasms, pancreatic neoplasms, gliomas, neoplasm metastases, and melanomas as the top five crucial disorders in this research area.
This research provides a comprehensive scientometric assessment, enhancing our understanding of NDDSs focused on ferroptosis. Consequently, it enables rapid access to essential information and facilitates the extraction of novel ideas in the field of ferroptotic nanomedicine for both experienced and emerging researchers.
在过去11年里，“基于铁死亡的纳米药物递送系统（NDDSs）”取得了显著进展。尽管目前缺乏全面的科学计量学概述和最新的科学图谱研究，特别是关于其演变、关键研究途径、当前研究格局、核心研究主题和未来方向的研究。
从科学网数据库获取2012年1月1日至2023年11月30日的数据。采用了各种先进的分析工具进行详细的科学计量学和可视化分析。
结果表明，中国在该领域占据显著领先地位，占总出版物的82.09%，从而在很大程度上塑造了该研究领域。陈宇是该领域发文量最多的作者。值得注意的是，该期刊的相关出版物数量最多。该研究确定肝癌、胰腺癌、神经胶质瘤、肿瘤转移和黑色素瘤是该研究领域的前五大关键疾病。
本研究提供了全面的科学计量学评估，加深了我们对聚焦铁死亡的纳米药物递送系统的理解。因此，它使经验丰富的研究人员和新兴研究人员都能够快速获取重要信息，并有助于在铁死亡纳米医学领域提取新的思路。
