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使用TENDYNE瓣膜经导管二尖瓣植入术治疗经导管二尖瓣缘对缘修复术后残留的严重二尖瓣反流:一例报告

Transcatheter mitral valve implantation using TENDYNE valve for the treatment of residual severe mitral regurgitation post-transcatheter mitral valve edge-to-edge repair: a case report.

作者信息

Abunab Mohammed Ali, Alamri Bandar Naim, Shah Muhammad Azam, Alshehri Halia Zain

机构信息

King Fahad Medical City, Dabab Street, Sulaimaniya, PO Box 221124, 11311 Riyadh, Saudi Arabia.

出版信息

Eur Heart J Case Rep. 2024 Sep 23;8(10):ytae515. doi: 10.1093/ehjcr/ytae515. eCollection 2024 Oct.

Abstract

BACKGROUND

Functional mitral regurgitation (MR) in patients with heart failure can be treated medically or by transcatheter edge-to-edge repair (TEER) if medical therapy fails. Patients who are not suitable for TEER or surgical intervention might benefit from transcatheter mitral valve implantation using the TENDYNE valve.

CASE SUMMARY

A 58-year-old male with a history of heart failure was admitted frequently with acute heart failure and functional MR, treated medically without significant improvement. He underwent mitral TEER therapy using MitraClip. A few months later, he was admitted with acute decompensated heart failure. Echocardiography showed severe MR with a detached clip from the posterior leaflet. He underwent redo mitral TEER using MitraClip as an option for treating single leaflet device detachment. He was readmitted with the same symptoms and his echocardiography showed detachment of both clips from the posterior leaflet. The patient underwent TMVI using the TENDYNE valve being not suitable for another attempt of mitral TEER. On follow-up, he was asymptomatic and echocardiography showed normal functioning mitral bioprosthesis with a mean gradient of 4 mm/Hg and no paravalvular leak.

DISCUSSION

Transcatheter mitral valve implantation using TENDYNE valve is an option for treating patients with functional MR and detached MitraClips.

摘要

背景

心力衰竭患者的功能性二尖瓣反流(MR)可通过药物治疗,若药物治疗失败,可采用经导管缘对缘修复术(TEER)。不适合TEER或外科干预的患者可能从使用TENDYNE瓣膜的经导管二尖瓣植入术中获益。

病例摘要

一名有心力衰竭病史的58岁男性因急性心力衰竭和功能性MR频繁入院,药物治疗效果不佳。他接受了使用MitraClip的二尖瓣TEER治疗。几个月后,他因急性失代偿性心力衰竭再次入院。超声心动图显示严重MR,夹子从后叶脱落。作为治疗单叶装置脱落的一种选择,他再次接受了使用MitraClip的二尖瓣TEER治疗。他再次因相同症状入院,超声心动图显示两个夹子均从后叶脱落。由于不适合再次尝试二尖瓣TEER,该患者接受了使用TENDYNE瓣膜的经导管二尖瓣植入术(TMVI)。随访时,他无症状,超声心动图显示二尖瓣生物瓣功能正常,平均压差为4 mm/Hg,无瓣周漏。

讨论

使用TENDYNE瓣膜进行经导管二尖瓣植入术是治疗功能性MR和MitraClip脱落患者的一种选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ba2/11463334/c86a4fb4c51c/ytae515il2.jpg

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