Cedirian Stephano, Alessandrini Aurora, Starace Michela V R
Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Skin Appendage Disord. 2024 Oct;10(5):342-356. doi: 10.1159/000538835. Epub 2024 May 22.
Pediatric nail disorders encompass a broad range of conditions. This article aimed to consolidate current knowledge on pediatric nail disorders to enhance diagnostic proficiency and clinical management among healthcare professionals.
Pediatric nail disorders present a diagnostic challenge due to their diverse nature. Non-syndromic congenital nail disorders encompass various anomalies such as anonychia/hyponychia, congenital malalignment of the great toenail, and racket thumbs, each with distinct clinical presentations and genetic associations. Syndromic congenital nail disorders, often part of complex syndromes, are characterized by unique features and associated abnormalities. Acquired nail diseases in children, like Beau's lines and onychomadesis, typically result from trauma or infection, while melanonychia, although rare in children, requires careful monitoring for potential malignant alterations, with consideration for biopsy in cases with concerning features.
(1) Pediatric nail disorders may pose diagnostic challenges and require a comprehensive understanding of nail anatomy and development. (2) Congenital nail disorders encompass isolated anomalies and syndromic associations, necessitating thorough evaluation for associated systemic conditions. (3) Acquired nail diseases may indicate underlying trauma or systemic illness and require careful assessment.(4) Melanonychia in children requires ongoing monitoring and evaluation, emphasizing the importance of consistent follow-up and histopathological examination when necessary.
儿童指甲疾病涵盖多种病症。本文旨在整合有关儿童指甲疾病的现有知识,以提高医疗保健专业人员的诊断能力和临床管理水平。
儿童指甲疾病因其多样性而带来诊断挑战。非综合征性先天性指甲疾病包括多种异常,如无甲/甲下皮缺失、拇趾先天性排列不齐和球拍状拇指,每种都有独特的临床表现和遗传关联。综合征性先天性指甲疾病通常是复杂综合征的一部分,具有独特特征和相关异常。儿童后天性指甲疾病,如博氏线和甲脱,通常由创伤或感染引起,而甲母痣虽然在儿童中罕见,但需要仔细监测是否有潜在的恶性改变,对于有可疑特征的病例需考虑活检。
(1)儿童指甲疾病可能带来诊断挑战,需要全面了解指甲解剖结构和发育情况。(2)先天性指甲疾病包括孤立异常和综合征关联,需要对相关全身状况进行全面评估。(3)后天性指甲疾病可能表明潜在的创伤或全身性疾病,需要仔细评估。(4)儿童甲母痣需要持续监测和评估,强调必要时进行持续随访和组织病理学检查的重要性。