Kinik Betul, Tural Onur Seda, Bicen Asli, Kara Kaan, Aker Cemal
Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Chest Disease, Zeytinburnu, 34760, Turkey.
Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Chest Surgery, Zeytinburnu, 34760, Turkey.
Respir Med Case Rep. 2024 Sep 21;52:102117. doi: 10.1016/j.rmcr.2024.102117. eCollection 2024.
Inflammatory myofibroblastic tumors (IMTs) are rare benign mesenchymal tumors that present diagnostic challenges due to their diverse clinical and radiological manifestations. We present a case of a 19-year-old female with a history of intermittent hemoptysis. Imaging studies suggested a mediobasal lung lesion, prompting further evaluation. Bronchoscopy revealed vascular changes, and PET imaging indicated high metabolic activity. A left lower lobectomy was performed for diagnostic and therapeutic purposes, confirming the diagnosis of IMT characterized by spindle cell proliferation and inflammatory infiltrates. Surgical resection remains the cornerstone treatment, offering favorable outcomes with rare recurrence. Follow-up underscores the importance of monitoring and assessing prognostic factors to optimize patient management.
炎性肌纤维母细胞瘤（IMTs）是罕见的良性间叶性肿瘤，因其多样的临床和影像学表现而带来诊断挑战。我们报告一例19岁女性病例，该患者有间歇性咯血病史。影像学检查提示肺中下叶病变，促使进一步评估。支气管镜检查发现血管改变，PET成像显示高代谢活性。为明确诊断和治疗，进行了左下肺叶切除术，确诊为以梭形细胞增殖和炎性浸润为特征的IMT。手术切除仍然是主要治疗方法，预后良好，复发罕见。随访强调监测和评估预后因素对优化患者管理的重要性。
