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肺肿瘤微波消融术后支气管胸膜瘘的处理:一例报告及文献复习

Management of bronchopleural fistula after microwave ablation of lung tumor: A case report and literature review.

作者信息

Meng Xiaopeng, Qiu Miao, Hu Liyong, Zhu Jianfang

机构信息

Department of Cardiothoracic Surgery, Shaoxing Second Hospital, Shaoxing, Zhejiang 312000, P.R. China.

Department of Tumor Radiotherapy, Shaoxing Second Hospital, Shaoxing, Zhejiang 312000, P.R. China.

出版信息

Exp Ther Med. 2024 Sep 30;28(6):443. doi: 10.3892/etm.2024.12732. eCollection 2024 Dec.

Abstract

Several patients with lung tumors are not eligible for surgical treatment. For those patients, percutaneous lung tumor ablation serves as a minimally invasive alternative to address such tumors. Despite its effectiveness, notable complications associated with this procedure can occur, such as bronchopleural fistula (BPF), which can lead to severe consequences. Therefore, the comprehensive understanding of these complications is of great importance for their safe and efficient management. In the present study, the case of a 73-year-old man with BPF following microwave ablation (MWA) of lung tumor and its clinical management was reported. MWA was performed after the diagnosis of lung cancer. Following ablation, the patient received thoracic drainage and anti-infectious therapy. After verifying the presence of BPF, an endobronchial unidirectional valve (EBV) was implanted into the posterior basal segment bronchus (B10) of the right lower lobe using a bronchoscope. EBV can occlude fistula while allowing drainage of secretions and trapped air. The function contributes to reducing infections around the fistula and promoting healing. The air leakage was stopped five days after EBV implantation and the thoracic drainage tube was then removed. At 86 days after EBV implantation, the pulmonary infection disappeared, while chest computed tomography scan revealed that the pulmonary necrotic cavity was narrowed. EBV implantation may have a higher successful rate compared with other endoscopic treatments for BPF.

摘要

几名肺部肿瘤患者不符合手术治疗条件。对于这些患者,经皮肺肿瘤消融术是一种治疗此类肿瘤的微创替代方法。尽管其有效,但该手术可能会出现一些显著的并发症,如支气管胸膜瘘(BPF),这可能会导致严重后果。因此,全面了解这些并发症对于其安全有效的管理至关重要。在本研究中,报告了一名73岁男性在肺肿瘤微波消融(MWA)后发生BPF的病例及其临床管理情况。肺癌诊断后进行了MWA。消融术后,患者接受了胸腔引流和抗感染治疗。在证实存在BPF后,使用支气管镜将支气管内单向阀(EBV)植入右下叶后基底段支气管(B10)。EBV可封闭瘘口,同时允许分泌物和潴留空气排出。该功能有助于减少瘘口周围的感染并促进愈合。EBV植入五天后漏气停止,随后拔除胸腔引流管。EBV植入86天后,肺部感染消失,而胸部计算机断层扫描显示肺坏死腔变窄。与其他治疗BPF的内镜治疗相比,EBV植入可能具有更高的成功率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85f4/11462390/1b2a2175a118/etm-28-06-12732-g00.jpg

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