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血液透析充分性指标Kt/V的测量方法及评估研究进展

Research progress on measurement methods and evaluation of the hemodialysis adequacy index Kt/V.

作者信息

Li Le-le, Xu Rui-Feng, He Ning, Hu Ta-la, Gao Wu-Niri, Wang Xi-Feng, Shi Dong-Ying, Zhao Jian-Rong, Meng Yan

机构信息

Department of Nephrology, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, China.

Department of Hemodialysis, The No. 2 Hospital of Hohhot, Hohhot, China.

出版信息

Ther Apher Dial. 2025 Feb;29(1):3-11. doi: 10.1111/1744-9987.14217. Epub 2024 Oct 10.

Abstract

The most common form of replacement therapy for end-stage renal disease (ESRD) is hemodialysis, and the adequacy of hemodialysis is strongly associated with the quality of life and long-term survival of patients. Kt/V is currently one of the most important indicators for evaluating the adequacy of hemodialysis. There are many methods for measuring Kt/V, such as blood collection and measurement, dialysate measurement, bioresistive resistance, WinNonlin software analysis, and artificial intelligence. There are different views on the importance of Kt/V as an indicator of the adequacy of hemodialysis. This article provides a literature review of the various methods of measuring Kt/V and on different perspectives on Kt/V as an evaluation of hemodialysis adequacy.

摘要

终末期肾病(ESRD)最常见的替代治疗形式是血液透析,而血液透析的充分性与患者的生活质量和长期生存率密切相关。Kt/V是目前评估血液透析充分性的最重要指标之一。测量Kt/V的方法有很多种,如采血测量、透析液测量、生物电阻抗、WinNonlin软件分析和人工智能。对于Kt/V作为血液透析充分性指标的重要性存在不同观点。本文对测量Kt/V的各种方法以及关于Kt/V作为血液透析充分性评估的不同观点进行了文献综述。

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