J Refract Surg. 2024 Oct;40(10):e716-e723. doi: 10.3928/1081597X-20240826-02. Epub 2024 Oct 1.
To assess the visual outcomes in patients with cataract implanted with a small-aperture intraocular lens (IOL) in eyes with aberrated corneas.
This prospective, non-interventional, single-center clinical study was conducted at Singapore National Eye Centre, Singapore. Twenty-one patients with aberrated corneas had IC-8 IOL (Bausch & Lomb, Inc) implantation. An aberrated cornea was defined as from natural causes: keratoconus (n = 1, 4.8%), high coma (n = 2, 9.5%), corneal scar (n = 1, 4.8%), or iatrogenic causes: keratorefractive procedure (n = 17, 86%). Uncorrected and corrected visual acuities were measured at distance (600 cm) (UDVA and CDVA), intermediate (66.7 cm) (UIVA and CIVA), and near (40 cm) (UNVA and CIVA). Defocus curve was tested monocularly and binocularly. Contrast sensitivity (CS) was measured under photopic and mesopic conditions with and without glare.
In IC-8 eyes, the mean ± standard deviation UDVA, UIVA, and UNVA was 0.24 ± 0.18, 0.19 ± 0.18, and 0.14 ± 0.14 logMAR, respectively. Mean CDVA, CIVA, and CNVA in IC-8 eyes was 0.12 ± 0.17, 0.16 ± 0.15, and 0.19 ± 0.13 logMAR, respectively. Binocular mean UDVA, UIVA, and UNVA was 0.07 ± 0.10, 0.07 ± 0.10, and 0.13 ± 0.12 logMAR, respectively. Defocus curve testing yielded a depth of focus of 1.50 D monocularly and 2.00 D binocularly at a 0.2 logMAR threshold. Photopic binocular CS with and without glare improved over monocular CS of IC-8 and fellow eyes under all spatial frequencies. Mesopic binocular CS with and without glare were similar among monocular IC-8 and fellow eyes across spatial frequencies. Most patients reported low levels of visual symptoms.
The IC-8 IOL provides good monocular and binocular visual outcomes for patients with cataract who had aberrated corneas. .
评估在角膜像差的患者中植入小光孔人工晶状体（IOL）后的视力结果。
本前瞻性、非干预性、单中心临床研究在新加坡国家眼科中心进行。21 例角膜像差患者植入了 IC-8 IOL（Bausch & Lomb，Inc）。角膜像差定义为：自然原因：圆锥角膜（n = 1，4.8%）、高彗差（n = 2，9.5%）、角膜瘢痕（n = 1，4.8%）或医源性原因：角膜屈光手术（n = 17，86%）。在远距离（600cm）（UDVA 和 CDVA）、中间距离（66.7cm）（UIVA 和 CIVA）和近距离（40cm）（UNVA 和 CIVA）测量未矫正和矫正视力。单眼和双眼测试离焦曲线。在明视和中视条件下，分别测量有无眩光的对比敏感度（CS）。
在 IC-8 眼中，平均±标准偏差 UDVA、UIVA 和 UNVA 分别为 0.24±0.18、0.19±0.18 和 0.14±0.14 logMAR。IC-8 眼中的平均 CDVA、CIVA 和 CNVA 分别为 0.12±0.17、0.16±0.15 和 0.19±0.13 logMAR。双眼平均 UDVA、UIVA 和 UNVA 分别为 0.07±0.10、0.07±0.10 和 0.13±0.12 logMAR。离焦曲线测试在 0.2 logMAR 阈值时，单眼和双眼的景深分别为 1.50D 和 2.00D。在所有空间频率下，明视双眼 CS 均优于单眼 IC-8 和对侧眼的 CS，且均有眩光。在所有空间频率下，中视双眼 CS 均无眩光，与单眼 IC-8 和对侧眼的 CS 相似。大多数患者报告视觉症状水平较低。
对于角膜像差的白内障患者，IC-8 IOL 可提供良好的单眼和双眼视觉效果。
