Emergence of drug-resistant clinical isolates in Myanmar.

Seven drug-resistant isolates were obtained from inpatients in three medical settings in Myanmar between February 2017 and January 2021. All isolates were resistant to β-lactams and colistin. Among these, four isolates were resistant to amikacin with minimum inhibitory concentration (MIC) of ≥64 µg ml. Six of the seven isolates harboured genes encoding intrinsic β-lactamases, including , and , whereas one isolate harboured , and an incomplete gene. Phylogenetic analysis based on whole-genome sequences revealed that several isolates in Myanmar formed their own clusters, whereas others were similar to isolates found in the USA. This is the first report of the emergence of species in Myanmar.