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在内镜逆行胰胆管造影术中注入二氧化碳而非碘化造影剂以显示胆总管。

Injection of carbon dioxide instead of iodinated contrast to display the common bile duct during endoscopic retrograde cholangiopancreatography.

作者信息

Liu Cui, Tian Lingyun, Ze Xingyu, Yang Ting, Wang Luowei, Li Zhaoshen

机构信息

Department of Gastroenterology, Digestive Endoscopy Center, Changhai Hospital, Naval Medical University, Shanghai, China.

Department of Gastroenterology, Digestive Endoscopy Center, Beijing Electric Power Hospital, State Grid Corporation of China, Capital Medical University, Beijing, China.

出版信息

J Minim Access Surg. 2025 Jan 1;21(1):83-85. doi: 10.4103/jmas.jmas_286_23. Epub 2024 Oct 9.

DOI:10.4103/jmas.jmas_286_23
PMID:39388215
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11838809/
Abstract

Common bile duct (CBD) stones are usually caused by biliary tract infection, biliary stricture, duodenal peripapillary diverticulum, Oddis sphincter dysfunction, and so on. Treatment is preferably with endoscopic retrograde cholangiopancreatography (ERCP), where an iodine-containing contrast agent is injected into the CBD to display the stone under fluoroscopy and then to confirm complete removal of the stone(s). We described a 65-year-old woman with CBD stones who had undergone cardiac pacemaker implantation and was allergic to iodinated contrast media. We performed ERCP + lithotomy + stent implantation under local anesthesia, with injection of carbon dioxide instead of iodinated contrast into the CBD, and successfully visualized the stones under fluoroscopy and then confirmed complete removal of them. The patient was generally in good condition without complications. Thus, we have demonstrated in this case report that carbon dioxide can be used as a safe, economical, and effective alternative to iodinated contrast agent during ERCP.

摘要

胆总管结石通常由胆道感染、胆管狭窄、十二指肠乳头周围憩室、Oddi括约肌功能障碍等引起。治疗首选内镜逆行胰胆管造影(ERCP),即将含碘造影剂注入胆总管,在荧光透视下显示结石,然后确认结石已完全取出。我们描述了一名65岁患有胆总管结石的女性,她已植入心脏起搏器且对碘化造影剂过敏。我们在局部麻醉下进行了ERCP + 取石术 + 支架植入术,向胆总管内注入二氧化碳而非碘化造影剂,成功在荧光透视下看到结石,随后确认结石已完全取出。患者总体状况良好,无并发症。因此,我们在本病例报告中证明,在ERCP期间,二氧化碳可作为碘化造影剂的一种安全、经济且有效的替代品。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/686b/11838809/de2442ceaec4/JMAS-21-83-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/686b/11838809/de2442ceaec4/JMAS-21-83-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/686b/11838809/de2442ceaec4/JMAS-21-83-g001.jpg

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本文引用的文献

1
Accuracy of carbon dioxide insufflation for endoscopic retrograde cholangiopancreatography using double-balloon endoscopy.使用双气囊内镜进行内镜逆行胰胆管造影时二氧化碳注入的准确性。
World J Gastroenterol. 2020 Nov 14;26(42):6669-6678. doi: 10.3748/wjg.v26.i42.6669.
2
CO or air cholangiography reduces the risk of post-ERCP cholangitis in patients with Bismuth type IV hilar biliary obstruction.经内镜逆行胰胆管造影(ERCP)术中行胆管 CO2 或空气造影,可降低胆系梗阻分型为Ⅳ型肝门部胆管梗阻的患者术后发生胆管炎的风险。
BMC Gastroenterol. 2020 Jun 15;20(1):189. doi: 10.1186/s12876-020-01341-9.
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Efficacy and safety of carbon dioxide insufflation versus air insufflation during endoscopic retrograde cholangiopancreatography in randomized controlled trials: a systematic review and meta-analysis.
随机对照试验中内镜逆行胰胆管造影术期间二氧化碳注入与空气注入的疗效和安全性:一项系统评价和荟萃分析。
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Adverse reactions to iodinated contrast media administered at the time of endoscopic retrograde cholangiopancreatography (ERCP).内镜逆行胰胆管造影术(ERCP)时使用碘化造影剂的不良反应。
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Iodinated contrast sensitivity in ERCP.
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