Rodriguez-Riascos Juan F, Rodriguez Whilman G, Porras-Meza Carlos A
IPS Colsubsidio Calle 63, Non-invasive Cardiology Department, Bogotá, Colombia.
IPS Colsubsidio Calle 63, Non-invasive Cardiology Department, Bogotá, Colombia.
J Electrocardiol. 2024 Nov-Dec;87:153812. doi: 10.1016/j.jelectrocard.2024.153812. Epub 2024 Oct 9.
Occurrence of nonsustained ventricular tachycardia (NSVT) is associated with negative outcomes. It is not clear whether specific electrocardiographic characteristics of premature ventricular contractions (PVCs) are associated with the occurrence of NSVT. The aim of this study was to identify electrocardiographic patterns associated with the presence of NSVT during 24-h electrocardiographic monitoring in patients with >10 PVCs per hour.
This was a retrospective, observational, cross-sectional study. We reviewed consecutive patients who received 24-h ECG monitoring performed at a single outpatient cardiology center. Patients who received 24-h electrocardiographic monitoring, with a PVC burden ≥10 PVCs/h were included. Occurrence of NSVT during 24-h electrocardiographic monitoring was the main outcome.
A total of 343 patients were analyzed (mean [SD] age, 69.7 [12.5] years; 177 men [51.6 %]). NSVT occurred in 72 patients who were compared with 271 patients without NSVT. The novel term "premature beat ratio", which aims to correlate the coupling interval and compensatory pause, was introduced; a value >0.5 was independently associated with NSVT according to the multivariate model (OR = 3.73, 95 % CI = 1.57-8.82; P = 0.002). PVC burden (OR = 1.09, 95 % CI = 1.02-1.17; P = 0.006), and triplets (OR = 18.19, 95 % CI = 7.32-45.18 P = 0.0) were also associated with NSVT in the multivariate model.
These findings suggest that patients with a high PVC burden, triplets, and a premature beat ratio greater than 0.5 have an increased probability of presenting with NSVT and may benefit from more rigorous follow-up.
非持续性室性心动过速（NSVT）的发生与不良预后相关。室性早搏（PVC）的特定心电图特征是否与NSVT的发生相关尚不清楚。本研究的目的是在每小时PVC>10次的患者进行24小时心电图监测期间，识别与NSVT存在相关的心电图模式。
这是一项回顾性、观察性横断面研究。我们回顾了在单一门诊心脏病中心接受24小时心电图监测的连续患者。纳入接受24小时心电图监测且PVC负荷≥10次/小时的患者。24小时心电图监测期间NSVT的发生是主要结局。
共分析了343例患者（平均[标准差]年龄，69.7[12.5]岁；177例男性[51.6%]）。72例患者发生NSVT，与271例未发生NSVT的患者进行比较。引入了旨在关联联律间期和代偿间歇的新术语“早搏比率”；根据多变量模型，该值>0.5与NSVT独立相关（OR=3.73，95%CI=1.57-8.82；P=0.002）。PVC负荷（OR=1.09，95%CI=1.02-1.17；P=0.006）和三联律（OR=18.19，95%CI=7.32-45.18，P=0.0）在多变量模型中也与NSVT相关。
这些发现表明，PVC负荷高、三联律以及早搏比率大于0.5的患者出现NSVT的可能性增加，可能受益于更严格的随访。
