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东非和中非地区腹腔镜胆囊切除术术后加速康复方案的实施与效果:卢旺达三级教学医院的一项前瞻性非随机对照试验

Implementation and outcomes of an enhanced recovery after surgery pathway for laparoscopic cholecystectomy in East and Central Africa: A prospective non-randomized controlled trial in Rwanda's Tertiary Teaching Hospital.

作者信息

Nyundo Martin, Kayondo King, Gasakure Miguel, Twagirumukiza Jean Damascene, Gashegu Julien, Detry Olivier

机构信息

Department of Surgery, University Teaching Hospital of Kigali, University of Rwanda, Kigali, Rwanda.

Department of Surgery, Rwanda Military Hospital, Kigali, Rwanda.

出版信息

World J Surg. 2025 Mar;49(3):605-614. doi: 10.1002/wjs.12371. Epub 2024 Oct 10.

Abstract

BACKGROUND

Enhanced recovery after surgery (ERAS) programs have demonstrated efficacy in optimizing perioperative care and improving patient outcomes in various surgeries. However, their implementation and outcomes in resource-limited settings remain underexplored. This study aimed to assess the implementation of an ERAS protocol for laparoscopic cholecystectomy in such a setting.

METHODS

This prospective non-randomized controlled trial involved 100 patients undergoing laparoscopic cholecystectomy at the University Teaching Hospital of Kigali, Rwanda. The first 50 patients on the ERAS pathway were prospectively evaluated and retrospectively compared to the last 50 patients operated on before ERAS implementation. Data on demographics, preoperative information, intraoperative compliance, postoperative events, and patient feedback were collected and analyzed.

RESULTS

ERAS implementation resulted in a significant reduction in hospital length of stay (LOS) (p < 0.001) without increase in complications. Compliance with ERAS principles, including preoperative education and perioperative management, was more than 90%. ERAS also reduced costs due to quicker recovery and shorter hospital LOS.

CONCLUSION

The implementation of ERAS for laparoscopic cholecystectomy in a limited-resource setting is feasible and safe, suggesting the possibility of its potential adoption in other abdominal procedures. A high level of adherence to the ERAS pathway can be achieved with effective patient education and the dedication of healthcare providers.

摘要

背景

术后加速康复(ERAS)方案已在优化各类手术的围手术期护理及改善患者预后方面显示出疗效。然而,其在资源有限环境中的实施情况及效果仍未得到充分探索。本研究旨在评估在这种环境下针对腹腔镜胆囊切除术实施ERAS方案的情况。

方法

这项前瞻性非随机对照试验纳入了卢旺达基加利大学教学医院100例行腹腔镜胆囊切除术的患者。对ERAS路径下的前50例患者进行前瞻性评估,并与ERAS实施前的最后50例手术患者进行回顾性比较。收集并分析了人口统计学数据、术前信息、术中依从性、术后事件及患者反馈。

结果

实施ERAS导致住院时间显著缩短(p < 0.001),且并发症未增加。对包括术前教育和围手术期管理在内的ERAS原则的依从率超过90%。ERAS还因恢复更快和住院时间缩短而降低了成本。

结论

在资源有限的环境中对腹腔镜胆囊切除术实施ERAS是可行且安全的,这表明其有可能应用于其他腹部手术。通过有效的患者教育和医护人员的奉献精神,可以实现对ERAS路径的高度依从。

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