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小儿年龄组终丝感染性表皮样囊肿;病例系列

Filum terminale infected epidermoid cysts in pediatric age group; A case series.

作者信息

Abdel Ghany Walid A, Hewedi Iman H, Halim George, Mahran Mostafa G, Talaat Sahar, Amin Saleh Dina, Al Karras Mazen T, Elhawi Mohamed E, Mahmoud Mohamed Ashraf, Nassef Marwa A, Ibrahim Aly

机构信息

Department of Neurosurgery, Ain Shams University, Cairo, Egypt.

Department of Pathology, Ain Shams University, Cairo, Egypt.

出版信息

World Neurosurg X. 2024 Sep 21;24:100408. doi: 10.1016/j.wnsx.2024.100408. eCollection 2024 Oct.

Abstract

BACKGROUND

Epidermoid cysts are rare and account for only 1 % of primary spinal tumors. It's due to inclusion of ectodermal tissue during the third and fourth weeks of gestation. Infected epidermoid cysts are exceedingly rare with very few reports in literature. The clinical presentations include radicular symptoms, motor weakness, sphincteric disturbance, and repeated chemical meningitis. Surgery of this kind of tumor remained a challenge and of a considerable recurrence rate.

METHODS

This is a retrospective study reviewing the records of six children who were treated for filum terminale infected epidermoid cysts. All patients underwent microsurgery, and the surgical outcomes were studied through a follow up period of at least 24 months.

RESULTS

All children had a low back dermal sinus with purulent discharge. One child was a recurrent presentation after the previous two surgeries for evacuation of pus collection, and the other five children were operated for the first time. All the six children had an associated neurological deficit; one child presented with active central nervous system infection, and one child had a history of meningitis and admission to hospital prior to our surgery. Regular follow up revealed no recurrence in any of the six patients. The five patients, who presented with motor weakness, showed significant improvement of the motor power with regular post-operative physical therapy.

CONCLUSION

Epidermoid cysts are rare benign lesions that may lead to significant morbidity when infected. The aim of microsurgical excision is to remove the cyst content and its capsule without inducing or increasing neurological deficit by the aid of intraoperative neuromonitoring and microsurgery techniques.

摘要

背景

表皮样囊肿罕见,仅占原发性脊柱肿瘤的1%。这是由于在妊娠第三和第四周时外胚层组织被包埋所致。感染性表皮样囊肿极为罕见,文献报道极少。临床表现包括神经根症状、运动无力、括约肌功能障碍和反复的化学性脑膜炎。这类肿瘤的手术仍然是一项挑战,且复发率相当高。

方法

这是一项回顾性研究,回顾了6例终丝感染性表皮样囊肿患儿的治疗记录。所有患者均接受了显微手术,并通过至少24个月的随访研究手术结果。

结果

所有患儿均有低位背部皮窦伴脓性分泌物。1例患儿在前两次手术引流脓液后复发,其他5例患儿首次手术。所有6例患儿均伴有神经功能缺损;1例患儿出现活动性中枢神经系统感染,1例患儿在我们手术前有脑膜炎病史并住院治疗。定期随访显示6例患者均无复发。5例出现运动无力的患者,通过术后定期物理治疗,运动能力有显著改善。

结论

表皮样囊肿是罕见的良性病变,感染时可能导致严重的发病率。显微手术切除的目的是在术中神经监测和显微手术技术的帮助下,清除囊肿内容物及其包膜,而不引起或增加神经功能缺损。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c35/11466641/66b3d872885d/gr1.jpg

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