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羧甲基纤维素：曲安奈德注射后速发型超敏反应中的一个隐匿元凶。

Carboxymethylcellulose: A hidden culprit in immediate hypersensitivity reactions after triamcinolone injections.

作者信息

Yan Aiwei, Fernandez Edward, Krantz Matthew Steven, Kahwash Basil M, Phillips Elizabeth J, Stone Cosby A

机构信息

Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.

出版信息

J Allergy Clin Immunol Glob. 2024 Sep 1;3(4):100337. doi: 10.1016/j.jacig.2024.100337. eCollection 2024 Nov.

DOI:10.1016/j.jacig.2024.100337
PMID:39391128
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11465078/
Abstract

We aim to bring awareness of allergies to excipients such as carboxymethylcellulose as "hidden dangers" that can be easily missed in diagnosis, leading to severe effects on patient health, and falsely limit the drug treatments that a patient can receive.

摘要

我们旨在提高人们对诸如羧甲基纤维素等辅料过敏的认识，将其视为诊断中容易被忽视的“隐患”，这些隐患会对患者健康产生严重影响，并错误地限制患者能够接受的药物治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e21/11465078/c691f920b906/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e21/11465078/c691f920b906/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e21/11465078/c691f920b906/gr1.jpg

相似文献

1
Carboxymethylcellulose: A hidden culprit in immediate hypersensitivity reactions after triamcinolone injections.羧甲基纤维素：曲安奈德注射后速发型超敏反应中的一个隐匿元凶。
J Allergy Clin Immunol Glob. 2024 Sep 1;3(4):100337. doi: 10.1016/j.jacig.2024.100337. eCollection 2024 Nov.
2
Hidden Dangers: Recognizing Excipients as Potential Causes of Drug and Vaccine Hypersensitivity Reactions.潜在危险：认识赋形剂作为药物和疫苗过敏反应的潜在原因。
J Allergy Clin Immunol Pract. 2021 Aug;9(8):2968-2982. doi: 10.1016/j.jaip.2021.03.002. Epub 2021 Mar 15.
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Carboxymethylcellulose excipient allergy: a case report.羧甲基纤维素赋形剂过敏：一例报告。
J Med Case Rep. 2021 Nov 24;15(1):565. doi: 10.1186/s13256-021-03180-y.
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[Anaphylactic shock after intradermal injection of corticosteroid].皮内注射皮质类固醇后发生过敏性休克
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Anaphylaxis following intralesional triamcinolone acetonide (Kenacort) injection.曲安奈德（康宁克通）皮损内注射后发生过敏反应。
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Anaphylaxis induced by the carboxymethylcellulose component of injectable triamcinolone acetonide suspension (Kenalog).注射用曲安奈德混悬液（康宁克通）中羧甲基纤维素成分引起的过敏反应。
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本文引用的文献

1
Anaphylaxis to Excipients in Current Clinical Practice: Evaluation and Management.当前临床实践中辅料的过敏反应：评估与管理。
Immunol Allergy Clin North Am. 2022 May;42(2):239-267. doi: 10.1016/j.iac.2021.12.008. Epub 2022 Mar 31.
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Recent Developments of Carboxymethyl Cellulose.羧甲基纤维素的最新进展
Polymers (Basel). 2021 Apr 20;13(8):1345. doi: 10.3390/polym13081345.
3
Hidden Dangers: Recognizing Excipients as Potential Causes of Drug and Vaccine Hypersensitivity Reactions.潜在危险：认识赋形剂作为药物和疫苗过敏反应的潜在原因。
J Allergy Clin Immunol Pract. 2021 Aug;9(8):2968-2982. doi: 10.1016/j.jaip.2021.03.002. Epub 2021 Mar 15.
4
"Idiopathic" anaphylaxis caused by carboxymethylcellulose in ice cream.冰淇淋中羧甲基纤维素引起的“特发性”过敏反应。
J Allergy Clin Immunol Pract. 2021 Jan;9(1):555-557.e1. doi: 10.1016/j.jaip.2020.10.051. Epub 2020 Nov 10.
5
Immediate Hypersensitivity to Polyethylene Glycols and Polysorbates: More Common Than We Have Recognized.对聚乙二醇和聚山梨酯的即刻过敏反应：比我们认识到的更为常见。
J Allergy Clin Immunol Pract. 2019 May-Jun;7(5):1533-1540.e8. doi: 10.1016/j.jaip.2018.12.003. Epub 2018 Dec 14.
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Indexed Pain Journals.索引疼痛期刊。
J Pain Palliat Care Pharmacother. 2008;22(1):45-46. doi: 10.1080/15360280801989377.
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Anaphylaxis from the carboxymethylcellulose component of barium sulfate suspension.硫酸钡混悬液中羧甲基纤维素成分引起的过敏反应。
N Engl J Med. 1997 Oct 30;337(18):1275-7. doi: 10.1056/NEJM199710303371804.
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Hypersensitivity to carboxymethyl-cellulose as a cause of anaphylactic reactions to drugs in cattle.
Nature. 1969 Aug 9;223(5206):621-3. doi: 10.1038/223621a0.