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威廉·科尔夫博士:人工肾脏之父。

Dr. Willem Kolff: The Father of the Artificial Kidney.

作者信息

Sharma Neeraj, Khav Eddie, Elahmadi Aisha, Ong John, Parag Sahil

机构信息

Department of Medicine, Division of Nephrology, University of Southern California Keck School of Medicine, Los Angeles, USA.

出版信息

Cureus. 2024 Sep 10;16(9):e69098. doi: 10.7759/cureus.69098. eCollection 2024 Sep.

Abstract

Dr. Willem J. Kolff (February 14, 1911-February 11, 2009) is widely considered the father of dialysis. In addition, his innovations also included the artificial heart and lung, which earned him the title "the Father of Artificial Organs". In due course, his artificial kidney evolved into modern dialysis, a procedure that filters and purifies blood using an extracorporeal circuit, now a life-sustaining treatment for patients with end-stage kidney failure. Furthermore, his membrane oxygenator, which provided a method to add oxygen to blood as it passed through a machine, is still used in heart-lung machines during open-heart surgery. He is also known for his work in developing the artificial heart (although it now carries the name of his student, Dr. Robert Jarvik), which was used in subsequent designs, as a bridge to heart transplantation. Thanks to his work on the artificial kidney, millions of patients worldwide have benefited from life-sustaining hemodialysis. It can also be argued that Dr. Kolff's introduction of dialysis in 1943 marks the dawn of modern nephrology.

摘要

威廉·J·科尔夫博士(1911年2月14日 - 2009年2月11日)被广泛认为是透析之父。此外,他的创新还包括人工心肺,这使他赢得了“人工器官之父”的称号。随着时间的推移,他的人工肾演变成了现代透析,这是一种利用体外循环过滤和净化血液的程序,如今已成为终末期肾衰竭患者的维持生命的治疗方法。此外,他的膜式氧合器,即一种在血液流经机器时向血液中添加氧气的方法,至今仍用于心脏直视手术中的心肺机。他还因在开发人工心脏方面的工作而闻名(尽管现在它以他的学生罗伯特·贾维克博士的名字命名),该人工心脏在后续设计中被用作心脏移植的桥梁。由于他在人工肾方面的工作,全球数百万患者受益于维持生命的血液透析。也可以说,科尔夫博士在1943年引入透析标志着现代肾脏病学的开端。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0579/11466315/4504908e242a/cureus-0016-00000069098-i01.jpg

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