Hydroxyapatite synthesis and characterization from marine sources: A comparative study.

BACKGROUND

Hydroxyapatite (HAP) is a biocompatible material widely used in biomedical applications. Recent studies have explored various marine sources for HAP synthesis, demonstrating its potential for diverse applications.

OBJECTIVE

This study aims to compare the characteristics of hydroxyapatite synthesized from sea shells and fish bones, specifically from the shells of (orange mud crab) and bones of (fourfinger threadfin).

MATERIALS & METHODS: HAP was synthesized from shells and bones. The synthesized HAP underwent comprehensive characterization, including scanning electron microscopy (SEM) for structural analysis, hemocompatibility testing, antibacterial assays, and energy-dispersive X-ray spectroscopy (EDS) analysis.

RESULTS

SEM revealed a complex structure of HAP with a clustered arrangement and biofilm-like features. HAP derived from crab shells exhibited superior structural properties compared to that from fish bones. Both sources demonstrated good hemocompatibility, essential for biomedical applications. The antibacterial assays indicated effective antibacterial properties for both HAP sources, with crab shell-derived HAP showing slightly better performance. EDS analysis confirmed the presence of key elements necessary for HAP, with a consistent composition in both sources.

CONCLUSION

Our study concludes that hydroxyapatite derived from shells exhibits superior properties compared to that from bones. This research establishes a precedent for future investigations into other marine species, thereby broadening the scope and potential of hydroxyapatite synthesis from natural sources.