Zerbi F, Biscaldi G P, Rivolta G L, Pugliese F, Tosca P
G Ital Med Lav. 1985 Mar-May;7(2-3):107-9.
Forty-four patients suffering from depressive disorders treated with lithium have been subdivide in two groups. One of groups included subjects with previous working anamnesis of exposure to renal toxic agents. The differences of renal function between the two groups have been considered. Significant differences of glomerular and tubular function have been found. These findings permit to hypothesize a synergism between lithium and nephrotoxic agents.
44 名接受锂治疗的抑郁症患者被分为两组。其中一组包括既往有接触肾毒性药物工作史的受试者。研究了两组之间的肾功能差异。发现肾小球和肾小管功能存在显著差异。这些发现使得可以推测锂与肾毒性药物之间存在协同作用。
