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初诊大 B 细胞淋巴瘤伴或不伴后续疾病进展的基因组特征。

Genomic Features of Newly Diagnosed Large B-cell Lymphoma with or without Subsequent Disease Progression.

机构信息

Lymphoma Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

出版信息

Cancer Res Commun. 2024 Nov 1;4(11):2947-2954. doi: 10.1158/2767-9764.CRC-24-0337.

Abstract

Genomic features of LBCL that can be detected by clinical laboratory assays may predict for resistance to first-line immunochemotherapy, as well as support the exploration of genomic features as biomarkers of response to therapies which could be offered to patients who experience disease progression.

摘要

LBCL 可通过临床实验室检测到的基因组特征可能预测对一线免疫化疗的耐药性,同时支持将基因组特征作为治疗反应的生物标志物进行探索,这些标志物可提供给经历疾病进展的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7194/11558615/429354633d3a/crc-24-0337_f1.jpg

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