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腔内激光消融治疗小隐静脉手术后形态复杂的静脉曲张复发的技术和早期结果。

Technique and early results of endovenous laser ablation in morphologically complex varicose vein recurrence after small saphenous vein surgery.

机构信息

Department of Vascular Surgery, Dermatologikum Hamburg GmbH, Hamburg, Germany.

Department of Vascular Medicine, University Heart and Vascular Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

出版信息

PLoS One. 2024 Oct 11;19(10):e0310182. doi: 10.1371/journal.pone.0310182. eCollection 2024.

Abstract

BACKGROUND

Recurrences after varicose vein treatment occur frequently and represent a significant health and economic problem. In contrast to primary treatments of superficial truncal venous insufficiency, their management is often more difficult. Here we assessed the technical feasibility and early results of endovenous laser ablation (EVLA) for recurrences with stumps or subfascial meandering varices after small saphenous vein (SSV) surgery.

METHODS

This single-center retrospective study included 45 consecutive EVLA procedures from July 2019 to December 2021 in 40 patients (19 male, 21 female, mean age 62.8 ± 12.7 years). Patients had clinically relevant recurrent varicose veins after SSV surgery, with clinical, etiologic, anatomic and pathophysiologic (CEAP) classification stage of C2S or higher. We categorized the recurrences morphologically according to duplex sonographic criteria. Ablations were done with a 1470 nanometers laser and dual ring radial fibers and aimed at thermal closure as proximal as possible to the upper inflow. Analyses were performed by descriptive statistics and the Kaplan-Meier method. The primary outcome analyzed was the technical success, defined by thermal occlusion not requiring re-intervention during the observation period. The secondary outcome was the occurrence of postoperative complications.

RESULTS

A complex morphology with residual stumps or tortuous venous connections to the popliteal vein was present in 35 cases (77.8%). Immediate technical success at the first postoperative visit after a median of 11 days (interquartile range 8-13 days) was 97.8%. During the follow-up period (median 77 days, interquartile range 13-256 days), 6 limbs (13.3%) required redo EVLA due to symptomatic persistent or newly presenting reflux. The median freedom from re-recurrence was 791 days. Otherwise, no medical or surgical complications requiring specific treatment were observed, particularly no endothermal heat-induced thrombosis (EHIT) or other thrombotic complications, and no nerve damage.

CONCLUSION

According to our pilot data, EVLA is technically feasible for complex popliteal variceal recurrence, although the success rate appears substantially lower than for primary treatment of truncal venous insufficiency.

摘要

背景

静脉曲张治疗后的复发很常见,是一个重大的健康和经济问题。与原发性浅静脉主干功能不全的治疗相比,其治疗往往更加困难。在此,我们评估了腔内激光消融术(EVLA)治疗大隐静脉手术后残留残端或皮下蜿蜒静脉引起的静脉曲张复发的技术可行性和早期结果。

方法

这是一项单中心回顾性研究,纳入了 2019 年 7 月至 2021 年 12 月间 40 例患者(19 名男性,21 名女性,平均年龄 62.8±12.7 岁)的 45 例连续 EVLA 手术。这些患者在大隐静脉手术后存在临床相关的静脉曲张复发,且临床、病因、解剖和病理生理学(CEAP)分类为 C2S 或更高。根据双功能超声标准,我们对复发的形态进行分类。消融采用 1470nm 激光和双环径向光纤进行,目的是在尽可能靠近上游流入处进行热闭合。分析采用描述性统计和 Kaplan-Meier 法。主要分析指标为技术成功率,定义为在观察期内无需再次干预的热闭塞。次要结果为术后并发症的发生情况。

结果

35 例(77.8%)存在复杂的形态,有残留残端或与腘静脉蜿蜒相连的静脉。术后 11 天(8-13 天)中位时间行首次术后随访时,即刻技术成功率为 97.8%。在中位随访 77 天(13-256 天)期间,6 条肢体(13.3%)因有症状的持续性或新出现的反流需要再次行 EVLA。无再复发的中位时间为 791 天。否则,未观察到需要特定治疗的其他医疗或手术并发症,特别是无热诱导血栓形成(EHIT)或其他血栓性并发症,也无神经损伤。

结论

根据我们的初步数据,EVLA 对复杂的腘静脉复发是可行的技术,但成功率似乎明显低于原发性主干静脉功能不全的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3944/11469504/b9012f09de2c/pone.0310182.g001.jpg

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