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小隐静脉再次热消融的成功率和预测因素。

Success rate and factors predictive of redo endothermal ablation of small saphenous veins.

机构信息

Vascular Institute of New York and the Division of Vascular Surgery, NYU Langone, Brooklyn, NY.

Vascular Institute of New York and the Division of Vascular Surgery, NYU Langone, Brooklyn, NY; Mayo Clinic, Rochester, Minn.

出版信息

J Vasc Surg Venous Lymphat Disord. 2022 Mar;10(2):395-401. doi: 10.1016/j.jvsv.2021.09.012. Epub 2021 Oct 27.

Abstract

OBJECTIVE

Endothermal ablation, such as endovenous laser ablation (EVLA) and radiofrequency ablation (RFA), has been increasingly used for treatment of small saphenous vein (SSV) insufficiency. Prior studies have shown recurrence rates of 0% to 10% in incompetent SSVs (ISSVs). The objective of the present study was to determine the efficacy of redo venous ablation for symptomatic recanalized SSVs and to predict the factors related to recanalization.

METHODS

A retrospective analysis of 2566 procedures in 1752 patients with chronic venous insufficiency due to ISSVs from 2012 to 2018 was performed, using individual medical record review for data extraction. All 2566 procedures were performed using endothermal ablation for patients in whom initial conservative management had failed. Postoperative duplex ultrasound scans were performed within 3 to 7 days after treatment. We defined successful obliteration as a lack of color flow using postoperative duplex ultrasound. We defined recanalization as the presence of reflux on duplex ultrasound in the target vessel during follow-up. We conducted follow-up examinations every 3 months during the first year and every 6 months subsequently.

RESULTS

Of the 2566 procedures, redo ablation was performed in 91 ISSVs for 86 patients, including 58 women and 28 men. Of the 91 procedures, 54 were performed on the left lower extremity and 37 on the right lower extremity. The mean body mass index was 32.2 ± 7.66 kg/m. The mean age was 62.4 ± 15.10 years. The CEAP (Clinical, Etiology, Anatomy, and Pathophysiology) class was C1, C2, C3, C4, C5, and C6 for 0, 0, 29, 43, 1, and 18 patients, respectively. The mean maximum diameter of the targeted veins for the redo procedures was 4.51 ± 1.33 mm. Of the 91 procedures, 40 were performed using EVLA and 51 were performed using RFA. The initial technical success was 98.9%. The redo procedures showed an early closure of 96.7%. At a mean follow-up duration of 24.9 ± 14.9 months, the closure rate was 96.5%. No correlation was found between successful obliteration with the redo procedure and age, gender, CEAP class, laterality, EVLA vs RFA, body mass index, or vein diameter.

CONCLUSIONS

The rates of successful closure for ISSVs with initial and redo procedures were comparable. These data have validated the potential usefulness of performing redo SSV ablation.

摘要

目的

热消融治疗,如静脉内激光消融术(EVLA)和射频消融术(RFA),已越来越多地用于治疗小隐静脉(SSV)功能不全。先前的研究显示,在功能不全的 SSV(ISSV)中复发率为 0%至 10%。本研究的目的是确定对于有症状再通的 SSV 进行静脉再消融的疗效,并预测与再通相关的因素。

方法

回顾性分析了 2012 年至 2018 年期间 1752 例因 ISSV 导致慢性静脉功能不全的 2566 例患者的 2566 例手术,通过单独的病历回顾提取数据。所有 2566 例手术均在初始保守治疗失败的患者中采用热消融治疗。治疗后 3 至 7 天内行术后双功超声检查。我们将术后双功超声未见彩色血流定义为闭塞成功。我们将随访期间目标血管内出现反流定义为再通。我们在术后第 1 年每 3 个月,随后每 6 个月进行一次随访检查。

结果

在 2566 例手术中,86 例 ISSV 患者(58 名女性和 28 名男性)进行了 91 次再消融。91 例手术中,54 例在左下肢,37 例在右下肢。平均 BMI 为 32.2 ± 7.66kg/m2。平均年龄为 62.4 ± 15.10 岁。CEAP(临床、病因、解剖和病理生理学)分级为 0、0、29、43、1 和 18 例患者分别为 C1、C2、C3、C4、C5 和 C6。再手术目标静脉的最大直径平均值为 4.51 ± 1.33mm。91 例手术中,40 例行 EVLA,51 例行 RFA。初始技术成功率为 98.9%。再手术早期闭塞率为 96.7%。在平均 24.9 ± 14.9 个月的随访中,闭塞率为 96.5%。再手术闭塞成功与年龄、性别、CEAP 分级、侧别、EVLA 与 RFA、BMI 或静脉直径之间无相关性。

结论

初始和再手术治疗 ISSV 的闭合成功率相当。这些数据验证了对 SSV 进行再消融的潜在有效性。

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